Bio-Rad Laboratories (BIO) vs Penumbra (PEN)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
Penumbra (PEN) has outperformed Bio-Rad Laboratories (BIO) over the past year, gaining 27.3% versus a gain of 24.1%. Over five years, PEN leads with a +18.2% price change compared with -49.0% for BIO. Penumbra is the larger company by market cap ($12.46 billion vs $9.84 billion), about 1.3 times the size.
On valuation, Bio-Rad Laboratories trades at a lower forward P/E (37.1x vs 51.6x for Penumbra). Bio-Rad Laboratories converts more of its revenue into profit, with a net margin of 29.4% versus 12.7%.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | BIO | PEN |
|---|---|---|
| Share price | $367.92 | $316.35 |
| Market cap | $9.84B | $12.46B |
| 1-day change | -0.25% | -0.22% |
| YTD return | +21.43% | +1.96% |
| 1-year return | +24.08% | +27.28% |
| 5-year return | -49.00% | +18.15% |
| P/E ratio (TTM) | 46.63 | 77.73 |
| Forward P/E | 37.10 | 51.59 |
| EPS (TTM) | $7.89 | $4.07 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | $2.58B | $1.40B |
| Revenue growth (YoY) | +0.65% | +17.50% |
| Net income (latest FY) | $759.90M | $177.69M |
| Gross margin | 51.87% | 67.14% |
| Operating margin | 1.83% | 13.48% |
| Net margin | 29.42% | 12.66% |
| 52-week high | $396.23 | $362.41 |
| 52-week low | $236.73 | $221.26 |
| Distance from 52-week high | -7.14% | -12.71% |
| Analyst consensus | hold | hold |
| Avg. price target upside | -10.76% | +14.30% |
| Average volume | 276.94K | 343.03K |
| Shares outstanding | 21.68M | 39.39M |
| Employees | 7,450 | 4,700 |
| Sector | Industrials | Health Care |
| Industry | Biotechnology: Laboratory Analytical Instruments | Medical/Dental Instruments |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Penumbra trades at a higher earnings multiple (77.7x vs 46.6x trailing P/E).
- Bio-Rad Laboratories is more profitable, keeping 29.4 cents of every revenue dollar as net income versus 12.7 cents for Penumbra.
- Penumbra grew revenue faster in its latest fiscal year (+17.50% vs +0.65%).
- The two companies sit in different sectors: Bio-Rad Laboratories in Industrials and Penumbra in Health Care.
About Bio-Rad Laboratories
BIO stock →Bio-Rad Laboratories, Inc. develops, manufactures, and distributes life science research and clinical diagnostic products in the United States, Europe, Asia, Canada, Latin America, and internationally.
Industrials · Biotechnology: Laboratory Analytical Instruments · 7,450 employees
About Penumbra
PEN stock →Penumbra, Inc., together with its subsidiaries, designs, develops, manufactures, and markets medical devices in the United States and internationally. It offers computer-assisted vacuum thrombectomy; peripheral thrombectomy products, including the Indigo System for power aspiration of thrombus in the body; Lightning Flash, a mechanical thrombectomy system; Lightning Bolt 7, an arterial thrombectomy system; and CAT RX.
Health Care · Medical/Dental Instruments · 4,700 employees
BIO vs PEN FAQ
Which is bigger, Bio-Rad Laboratories or Penumbra?
Penumbra (PEN) is larger, with a market capitalization of $12.46B compared with $9.84B for Bio-Rad Laboratories (BIO).
Which stock has performed better over the past year, BIO or PEN?
PEN returned +27.28% over the past 12 months, compared with +24.08% for BIO (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, BIO or PEN?
BIO has the lower trailing P/E at 46.6, versus 77.7 for PEN. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Bio-Rad Laboratories and Penumbra in the same industry?
No. Bio-Rad Laboratories is in the Industrials sector, while Penumbra is in Health Care.