CareDx (CDNA) vs Sotera Health (SHC)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
CareDx (CDNA) has outperformed Sotera Health (SHC) over the past year, gaining 331.6% versus a gain of 11.3%. Over five years, CDNA leads with a -11.2% price change compared with -31.5% for SHC. Sotera Health is the larger company by market cap ($5.11 billion vs $3.26 billion), about 1.6 times the size.
On valuation, Sotera Health trades at a lower forward P/E (16.7x vs 48.9x for CareDx).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | CDNA | SHC |
|---|---|---|
| Share price | $63.04 | $17.90 |
| Market cap | $3.26B | $5.11B |
| 1-day change | -1.18% | -1.92% |
| YTD return | +236.09% | +1.47% |
| 1-year return | +331.63% | +11.32% |
| 5-year return | -11.21% | -31.55% |
| P/E ratio (TTM) | 30.31 | 31.40 |
| Forward P/E | 48.87 | 16.65 |
| EPS (TTM) | $2.08 | $0.57 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | — | $1.16B |
| Revenue growth (YoY) | — | +5.74% |
| Net income (latest FY) | — | $77.95M |
| Gross margin | — | 55.48% |
| Net margin | — | 6.70% |
| 52-week high | $72.51 | $19.85 |
| 52-week low | $13.95 | $13.09 |
| Distance from 52-week high | -13.06% | -9.82% |
| Analyst consensus | buy | buy |
| Avg. price target upside | -6.68% | +26.93% |
| Average volume | 1.28M | 2.54M |
| Shares outstanding | 51.73M | 285.37M |
| Employees | 761 | 3,000 |
| Sector | Health Care | Health Care |
| Industry | Medical Specialities | Misc Health and Biotechnology Services |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- CDNA has outperformed SHC by 320.3 percentage points over the past year.
About CareDx
CDNA stock →CareDx, Inc. provides solutions for improving outcomes for transplant patients and advancing organ health in the United States and internationally.
Health Care · Medical Specialities · 761 employees
About Sotera Health
SHC stock →Sotera Health Company provides sterilization solutions, lab testing, and advisory services for the healthcare industry in the United States, Canada, Europe, and internationally. The company operates through three segments: Sterigenics, Nordion, and Nelson Labs.
Health Care · Misc Health and Biotechnology Services · 3,000 employees
CDNA vs SHC FAQ
Which is bigger, CareDx or Sotera Health?
Sotera Health (SHC) is larger, with a market capitalization of $5.11B compared with $3.26B for CareDx (CDNA).
Which stock has performed better over the past year, CDNA or SHC?
CDNA returned +331.63% over the past 12 months, compared with +11.32% for SHC (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, CDNA or SHC?
CDNA has the lower trailing P/E at 30.3, versus 31.4 for SHC. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are CareDx and Sotera Health in the same industry?
Both are in the Health Care sector, but in different industries: Medical Specialities for CareDx and Misc Health and Biotechnology Services for Sotera Health.