MetaCap

Silence Therapeutics Plc American Depository Share (SLN) vs Shattuck Labs (STTK)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.

Summary

Shattuck Labs (STTK) has outperformed Silence Therapeutics Plc American Depository Share (SLN) over the past year, gaining 130.8% versus a gain of 91.1%. Over five years, SLN leads with a -55.0% price change compared with -70.7% for STTK. Silence Therapeutics Plc American Depository Share is the larger company by market cap ($610.4 million vs $567.6 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

SLN+89.21%STTK+118.34%
+223%+90%-44%
Oct 6, 20251 yearOct 7, 2026
SLN-53.42%STTK-71.91%
+28%-37%-102%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

SLN versus STTK key metrics
MetricSLNSTTK
Share price$9.82$5.66
Market cap$610.35M$567.55M
1-day change-0.10%-3.50%
YTD return+61.51%+54.93%
1-year return+91.05%+130.82%
5-year return-55.00%-70.74%
EPS (TTM)$-1.29$-0.47
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$17.58$8.33
52-week low$4.19$1.70
Distance from 52-week high-44.13%-32.11%
Average volume1.11M1.20M
Shares outstanding62.15M100.36M
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • STTK has outperformed SLN by 39.8 percentage points over the past year.

SLN vs STTK FAQ

Which is bigger, Silence Therapeutics Plc American Depository Share or Shattuck Labs?

Silence Therapeutics Plc American Depository Share (SLN) is larger, with a market capitalization of $610.35M compared with $567.55M for Shattuck Labs (STTK).

Which stock has performed better over the past year, SLN or STTK?

STTK returned +130.82% over the past 12 months, compared with +91.05% for SLN (price return, excluding dividends). Past performance does not predict future results.

Are Silence Therapeutics Plc American Depository Share and Shattuck Labs in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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