Health ETFs
44 health ETFs ranked by assets under management. Updated October 10, 2026.
Total assets
$91.8B
MetaCap lists 44 US-listed ETFs in the Health category, holding a combined $91.8B in assets. The largest by assets are XLV ($43.4B), IBB ($11.2B) and XBI ($10.4B). Expense ratios range from 0.08% to 2.56% (median 0.47%); XLV is the lowest-cost fund shown at 0.08% a year. On the latest trading day, 43 of 44 funds were higher, with an average move of +2.15%.
Summary generated from market data by MetaCap's automated system. Methodology
Largest health ETFs by assets
| # | Symbol | Fund Name | Price | % Change | AUM |
|---|---|---|---|---|---|
| 1 | XLV | State Street Health Care Select Sector SPDR ETF | 170.81 | +1.58% | $43.39B |
| 2 | IBB | iShares Biotechnology ETF | 206.49 | +3.00% | $11.20B |
| 3 | XBI | State Street SPDR S&P Biotech ETF | 153.77 | +3.00% | $10.36B |
| 4 | IXJ | iShares Global Healthcare ETF | 103.17 | +1.37% | $4.32B |
| 5 | FHLC | Fidelity MSCI Health Care Index ETF | 82.45 | +1.61% | $3.54B |
| 6 | IHI | iShares U.S. Medical Devices ETF | 51.74 | +1.25% | $3.45B |
| 7 | FBT | First Trust Amex Biotech Index Fund | 265.40 | +2.00% | $2.97B |
| 8 | ARKG | ARK Genomic Revolution ETF | 51.30 | +4.08% | $2.22B |
| 9 | IHE | iShares U.S. Pharmaceutical ETF | 100.09 | +1.24% | $1.63B |
| 10 | IHF | iShares U.S. Health Care Providers ETF | 56.76 | +1.74% | $1.36B |
| 11 | FTXH | First Trust Nasdaq Pharmaceuticals ETF | 41.27 | +2.03% | $1.06B |
| 12 | PBPH | Portfolio Building Block World Pharma and Biotech Index ETF | 28.36 | +1.38% | $1.05B |
| 13 | PPH | VanEck Pharmaceutical ETF | 110.49 | +1.20% | $1.02B |
| 14 | PJP | Invesco Pharmaceuticals ETF | 122.88 | +1.56% | $557.24M |
| 15 | XPH | State Street SPDR S&P Pharmaceuticals ETF | 64.65 | +1.60% | $523.98M |
| 16 | BBH | VanEck Biotech ETF | 240.47 | +2.85% | $487.74M |
| 17 | PBE | Invesco Biotechnology & Genome ETF | 96.90 | +2.80% | $423.52M |
| 18 | PTH | Invesco Dorsey Wright Healthcare Momentum ETF | 58.76 | +2.45% | $366.97M |
| 19 | PINK | Simplify Health Care ETF | 38.53 | +2.57% | $348.96M |
| 20 | IDNA | iShares Genomics Immunology and Healthcare ETF | 42.17 | +4.33% | $298.98M |
| 21 | XHS | State Street SPDR S&P Health Care Services ETF | 136.03 | +1.05% | $218.48M |
| 22 | CANC | Tema Oncology ETF | 40.78 | +1.50% | $208.60M |
| 23 | BBP | Virtus Biotech ETF | 104.76 | +3.48% | $131.53M |
| 24 | LFSC | F/m Emerald Life Sciences Innovation ETF | 42.61 | +2.71% | $123.35M |
| 25 | IBBQ | Invesco Nasdaq Biotechnology ETF | 34.62 | +3.01% | $103.28M |
| 26 | GNOM | Global X Genomics & Biotechnology ETF | 68.75 | +4.44% | $102.88M |
| 27 | SURI | Simplify Propel Opportunities ETF | 17.22 | +0.78% | $76.30M |
| 28 | OZEM | Roundhill GLP-1 & Weight Loss ETF | 29.60 | +1.20% | $57.76M |
| 29 | HRTS | Tema Heart & Health ETF | 36.22 | +1.87% | $53.71M |
| 30 | FMED | Fidelity Disruptive Medicine ETF | 31.40 | +3.19% | $52.31M |
| 31 | MEDI | Harbor Health Care ETF | 32.46 | +1.75% | $41.69M |
| 32 | TMED | T. Rowe Price Health Care ETF | 33.81 | +3.33% | $33.01M |
| 33 | GDOC | Goldman Sachs Future Health Care Equity ETF | 36.50 | +1.53% | $19.48M |
| 34 | BMED | iShares Health Innovation Active ETF | 34.34 | +2.04% | $13.80M |
| 35 | IBRN | iShares Neuroscience and Healthcare ETF | 31.75 | +1.15% | $6.65M |
| 36 | WDNA | WisdomTree BioRevolution Fund | 23.50 | +3.98% | $4.80M |
| 37 | EKG | First Trust Nasdaq Lux Digital Health Solutions ETF | 23.42 | +3.30% | $4.74M |
| 38 | NVOH | Novo Nordisk A/S B Shares ADRhedged | 21.79 | +0.54% | $3.60M |
| 39 | GNMX | Corgi Genomics & Precision Medicine ETF | 37.52 | +3.90% | $2.87M |
| 40 | LGHT | Langar Global HealthTech ETF | 10.81 | +3.52% | $2.40M |
| 41 | MHIP | Milliman Healthcare Inflation Plus ETF | 20.84 | +1.11% | $1.55M |
| 42 | ASD | Defiance Autism Impact ETF | 26.62 | +0.62% | $1.34M |
| 43 | GSKH | GSK plc ADRhedged | 66.29 | -0.10% | $682.76K |
| 44 | TRUH | VanEck Healthcare TruSector ETF | 29.78 | +1.11% | $589.45K |
Frequently asked questions
- How many health ETFs are there?
- MetaCap tracks 44 US-listed health ETFs with about $91.8B in combined assets.
- What is the largest health ETF?
- State Street Health Care Select Sector SPDR ETF (XLV) is the largest, with about $43.4B in assets under management.
- Which Health ETF has the lowest expense ratio?
- Among the funds shown, State Street Health Care Select Sector SPDR ETF (XLV) has the lowest expense ratio at 0.08% per year, or $8 a year on a $10,000 investment.
- What does AUM mean for an ETF?
- Assets under management (AUM) is the total market value of everything the fund holds. Larger ETFs tend to have tighter bid-ask spreads and more trading volume, but size alone does not make a fund a better investment.
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Prices as of Oct 10, 4:50 AM EDT. Market data is delayed at least 15 minutes and provided for informational purposes only. Not investment advice. Full disclaimer