MetaCap

AbbVie (ABBV) vs Pfizer (PFE)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.

Summary

AbbVie (ABBV) has outperformed Pfizer (PFE) over the past year, gaining 16.5% versus a gain of 6.6%. Over five years, ABBV leads with a +148.2% price change compared with -32.5% for PFE. AbbVie is the larger company by market cap ($479.52 billion vs $159.59 billion), about 3.0 times the size.

On valuation, Pfizer trades at a lower forward P/E (9.7x vs 16.7x for AbbVie). Pfizer offers the higher dividend yield (6.14% vs 2.52%). Pfizer converts more of its revenue into profit, with a net margin of 12.4% versus 6.9%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ABBV+16.55%PFE+6.59%
+18%+1%-17%
Oct 7, 20251 yearOct 7, 2026
ABBV+144.07%PFE-34.04%
+154%+48%-58%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ABBV versus PFE key metrics
MetricABBVPFE
Share price$271.36$28.00
Market cap$479.52B$159.59B
1-day change+1.75%+1.82%
YTD return+18.76%+12.45%
1-year return+16.55%+6.59%
5-year return+148.20%-32.51%
P/E ratio (TTM)76.6636.84
Forward P/E16.699.67
EPS (TTM)$3.54$0.76
Dividend yield2.52%6.14%
Annual dividend$6.83$1.72
Revenue (latest FY)$61.16B$62.58B
Revenue growth (YoY)+8.57%-1.65%
Net income (latest FY)$4.23B$7.77B
Gross margin70.24%74.33%
Operating margin24.65%—
Net margin6.91%12.42%
52-week high$274.94$29.21
52-week low$190.75$23.62
Distance from 52-week high-1.30%-4.14%
Analyst consensusbuybuy
Avg. price target upside+3.48%+3.25%
Average volume4.86M36.02M
Shares outstanding1.77B5.70B
Employees57,00075,000
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AbbVie is about 3.0 times larger than Pfizer by market value ($479.52B vs $159.59B).
  • AbbVie trades at a higher earnings multiple (76.7x vs 36.8x trailing P/E).
  • Pfizer offers a meaningfully higher dividend yield (6.14% vs 2.52%).
  • Pfizer is more profitable, keeping 12.4 cents of every revenue dollar as net income versus 6.9 cents for AbbVie.
  • AbbVie grew revenue faster in its latest fiscal year (+8.57% vs -1.65%).

About AbbVie

ABBV stock →

AbbVie Inc., a research-based biopharmaceutical company, engages in the research and development, manufacturing, commercializing, and sale of medicines and therapies worldwide. The company offers Skyrizi to treat autoimmune diseases; Rinvoq to treat inflammatory diseases; Imbruvica for the treatment of adult patients with blood cancers; Venclexta to treat blood cancers; Elahere to treat various cancer; and Epkinly to treat lymphoma; and Emrelis for the treatment of lung cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 57,000 employees

About Pfizer

PFE stock →

Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 75,000 employees

ABBV vs PFE FAQ

Which is bigger, AbbVie or Pfizer?

AbbVie (ABBV) is larger, with a market capitalization of $479.52B compared with $159.59B for Pfizer (PFE).

Which stock has performed better over the past year, ABBV or PFE?

ABBV returned +16.55% over the past 12 months, compared with +6.59% for PFE (price return, excluding dividends). Past performance does not predict future results.

Which has the lower P/E ratio, ABBV or PFE?

PFE has the lower trailing P/E at 36.8, versus 76.7 for ABBV. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.

Which pays a higher dividend, AbbVie or Pfizer?

Pfizer has the higher yield at 6.14%, compared with 2.52% for AbbVie.

Are AbbVie and Pfizer in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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