MetaCap

Abeona Therapeutics (ABEO) vs Bicycle Therapeutics (BCYC)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

Abeona Therapeutics (ABEO) has outperformed Bicycle Therapeutics (BCYC) over the past year, losing 12.7% versus a loss of 56.1%. Over five years, ABEO leads with a -78.3% price change compared with -93.4% for BCYC. Abeona Therapeutics is the larger company by market cap ($282.5 million vs $272.3 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ABEO-12.72%BCYC-56.14%
+36%-15%-67%
Oct 9, 20251 yearOct 9, 2026
ABEO-79.20%BCYC-92.63%
+21%-39%-99%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ABEO versus BCYC key metrics
MetricABEOBCYC
Share price$4.94$3.89
Market cap$282.49M$272.27M
1-day change-0.40%+2.10%
YTD return-6.26%-45.06%
1-year return-12.72%-56.14%
5-year return-78.29%-93.44%
EPS (TTM)$-1.18$-2.73
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.65$9.10
52-week low$4.00$3.33
Distance from 52-week high-35.42%-57.25%
Analyst consensusstrong_buynone
Avg. price target upside+282.19%+144.22%
Average volume1.39M387.29K
Shares outstanding57.18M50.55M
Employees226288
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ABEO has outperformed BCYC by 43.4 percentage points over the past year.

About Abeona Therapeutics

ABEO stock →

Abeona Therapeutics Inc., a commercial-stage biopharmaceutical company, develops gene and cell therapies for life-threatening diseases in the United States. It develops ZEVASKYN, an autologous, cell-based gene therapy for the treatment of patients with recessive dystrophic epidermolysis bullosa.

Health Care · Biotechnology: Pharmaceutical Preparations · 226 employees

About Bicycle Therapeutics

BCYC stock →

Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company's products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase II clinical trials for the treatment of high nectin-4 expressing tumors; nuzefatide pevedotin (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle tumor-targeted immune cell agonist molecule, which is in phase I/II targeting nectin-4 and agonizing CD137; and BT1702, a theranostic BRC molecule targeting MT1-MMP for which IND-enabling activities are ongoing.

Health Care · Biotechnology: Pharmaceutical Preparations · 288 employees

ABEO vs BCYC FAQ

Which is bigger, Abeona Therapeutics or Bicycle Therapeutics?

Abeona Therapeutics (ABEO) is larger, with a market capitalization of $282.49M compared with $272.27M for Bicycle Therapeutics (BCYC).

Which stock has performed better over the past year, ABEO or BCYC?

ABEO returned -12.72% over the past 12 months, compared with -56.14% for BCYC (price return, excluding dividends). Past performance does not predict future results.

Are Abeona Therapeutics and Bicycle Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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