MetaCap

Abeona Therapeutics (ABEO) vs Prelude Therapeutics (PRLD)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Prelude Therapeutics (PRLD) has outperformed Abeona Therapeutics (ABEO) over the past year, gaining 166.0% versus a loss of 3.2%. Over five years, PRLD leads with a -76.4% price change compared with -77.7% for ABEO. Prelude Therapeutics is the larger company by market cap ($309.6 million vs $283.6 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ABEO-3.24%PRLD+165.97%
+379%+170%-40%
Oct 7, 20251 yearOct 7, 2026
ABEO-78.61%PRLD-75.87%
+16%-42%-101%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ABEO versus PRLD key metrics
MetricABEOPRLD
Share price$4.96$3.88
Market cap$283.63M$309.64M
1-day change-2.36%+1.31%
YTD return-3.61%+32.07%
1-year return-3.24%+165.97%
5-year return-77.67%-76.45%
EPS (TTM)$-1.18$-0.73
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.65$6.83
52-week low$4.00$1.15
Distance from 52-week high-35.16%-43.19%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+280.65%+137.11%
Average volume1.41M477.45K
Shares outstanding57.18M65.08M
Employees22679
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PRLD has outperformed ABEO by 169.2 percentage points over the past year.

About Abeona Therapeutics

ABEO stock →

Abeona Therapeutics Inc., a commercial-stage biopharmaceutical company, develops gene and cell therapies for life-threatening diseases in the United States. It develops ZEVASKYN, an autologous, cell-based gene therapy for the treatment of patients with recessive dystrophic epidermolysis bullosa.

Health Care · Biotechnology: Pharmaceutical Preparations · 226 employees

About Prelude Therapeutics

PRLD stock →

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET.

Health Care · Biotechnology: Pharmaceutical Preparations · 79 employees

ABEO vs PRLD FAQ

Which is bigger, Abeona Therapeutics or Prelude Therapeutics?

Prelude Therapeutics (PRLD) is larger, with a market capitalization of $309.64M compared with $283.63M for Abeona Therapeutics (ABEO).

Which stock has performed better over the past year, ABEO or PRLD?

PRLD returned +165.97% over the past 12 months, compared with -3.24% for ABEO (price return, excluding dividends). Past performance does not predict future results.

Are Abeona Therapeutics and Prelude Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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