MetaCap

Acumen Pharmaceuticals (ABOS) vs Tenaya Therapeutics (TNYA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Acumen Pharmaceuticals (ABOS) has outperformed Tenaya Therapeutics (TNYA) over the past year, gaining 11.7% versus a loss of 70.3%. Over five years, ABOS leads with a -84.5% price change compared with -97.4% for TNYA. Acumen Pharmaceuticals is the larger company by market cap ($151.9 million vs $122.0 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ABOS+11.70%TNYA-70.26%
+87%+4%-78%
Oct 8, 20251 yearOct 8, 2026
ABOS-84.39%TNYA-97.72%
+19%-42%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ABOS versus TNYA key metrics
MetricABOSTNYA
Share price$2.10$0.5442
Market cap$151.87M$122.03M
1-day change0.00%+2.02%
YTD return-0.47%-23.57%
1-year return+11.70%-70.26%
5-year return-84.50%-97.35%
EPS (TTM)$-1.64$-0.52
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.60$2.35
52-week low$1.50$0.5211
Distance from 52-week high-41.67%-76.84%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+261.90%+488.02%
Average volume439.10K2.26M
Shares outstanding72.32M224.23M
Employees6070
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ABOS has outperformed TNYA by 82.0 percentage points over the past year.

About Acumen Pharmaceuticals

ABOS stock →

Acumen Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops targeted therapies for the treatment of Alzheimer's disease. It focuses on advancing a targeted immunotherapy drug candidate, sabirnetug (ACU193), which is in its Phase 2 ALTITUDE-AD clinical trial to target toxic soluble amyloid beta oligomers.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 60 employees

About Tenaya Therapeutics

TNYA stock →

Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 70 employees

ABOS vs TNYA FAQ

Which is bigger, Acumen Pharmaceuticals or Tenaya Therapeutics?

Acumen Pharmaceuticals (ABOS) is larger, with a market capitalization of $151.87M compared with $122.03M for Tenaya Therapeutics (TNYA).

Which stock has performed better over the past year, ABOS or TNYA?

ABOS returned +11.70% over the past 12 months, compared with -70.26% for TNYA (price return, excluding dividends). Past performance does not predict future results.

Are Acumen Pharmaceuticals and Tenaya Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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