MetaCap

Arbutus Biopharma (ABUS) vs Alto Neuroscience (ANRO)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Alto Neuroscience (ANRO) has outperformed Arbutus Biopharma (ABUS) over the past year, gaining 296.0% versus a gain of 0.0%. Alto Neuroscience is the larger company by market cap ($923.0 million vs $657.6 million), about 1.4 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ABUS0.00%ANRO+295.96%
+543%+251%-41%
Oct 7, 20251 yearOct 7, 2026
ABUS+80.25%ANRO+13.62%
+129%+14%-102%
Jan 29, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ABUS versus ANRO key metrics
MetricABUSANRO
Share price$4.29$23.52
Market cap$657.55M$922.97M
1-day change-4.24%-0.72%
YTD return-10.81%+32.13%
1-year return0.00%+295.96%
5-year return+5.15%—
P/E ratio (TTM)5.43—
EPS (TTM)$0.79$-2.31
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$5.45$37.48
52-week low$3.50$5.23
Distance from 52-week high-21.28%-37.25%
Analyst consensusnonestrong_buy
Avg. price target upside+24.71%+63.18%
Average volume4.68M543.14K
Shares outstanding153.28M39.24M
Employees1968
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ANRO has outperformed ABUS by 296.0 percentage points over the past year.

About Arbutus Biopharma

ABUS stock →

Arbutus Biopharma Corporation, a clinical-stage biopharmaceutical company, develops novel therapeutics for infectious disease in the United States. Its chronic Hepatitis B virus product pipeline comprises Imdusiran, conjugated GalNAc, subcutaneously-delivered RNAi therapeutic product candidate which is in phase 2a clinical trials that suppresses all HBV antigens, including HBsAg expression; and AB-101, an oral PD-L1 inhibitor, which is in phase 1a/1b clinical trial that has the potential to reawaken patients' HBV-specific immune response by inhibiting PD-L1.

Health Care · Biotechnology: Pharmaceutical Preparations · 19 employees

About Alto Neuroscience

ANRO stock →

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States.

Health Care · Biotechnology: Pharmaceutical Preparations · 68 employees

ABUS vs ANRO FAQ

Which is bigger, Arbutus Biopharma or Alto Neuroscience?

Alto Neuroscience (ANRO) is larger, with a market capitalization of $922.97M compared with $657.55M for Arbutus Biopharma (ABUS).

Which stock has performed better over the past year, ABUS or ANRO?

ANRO returned +295.96% over the past 12 months, compared with 0.00% for ABUS (price return, excluding dividends). Past performance does not predict future results.

Are Arbutus Biopharma and Alto Neuroscience in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

More comparisons