MetaCap

Aclaris Therapeutics (ACRS) vs Aquestive Therapeutics (AQST)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

Aclaris Therapeutics (ACRS) has outperformed Aquestive Therapeutics (AQST) over the past year, gaining 96.4% versus a loss of 28.6%. Over five years, AQST leads with a +23.5% price change compared with -77.2% for ACRS. Aquestive Therapeutics is the larger company by market cap ($599.9 million vs $563.8 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ACRS+96.41%AQST-28.55%
+250%+90%-70%
Oct 9, 20251 yearOct 9, 2026
ACRS-78.66%AQST+29.54%
+101%-2%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ACRS versus AQST key metrics
MetricACRSAQST
Share price$3.83$4.78
Market cap$563.77M$599.95M
1-day change+1.06%+0.42%
YTD return+27.24%-26.01%
1-year return+96.41%-28.55%
5-year return-77.22%+23.51%
EPS (TTM)$-0.58$-0.66
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$6.60$7.55
52-week low$1.74$2.93
Distance from 52-week high-41.97%-36.69%
Analyst consensusstrong_buynone
Avg. price target upside+165.80%+95.19%
Average volume2.61M2.67M
Shares outstanding147.20M125.51M
Employees69147
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ACRS has outperformed AQST by 125.0 percentage points over the past year.

About Aclaris Therapeutics

ACRS stock →

Aclaris Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovering and developing novel molecule product candidates for immuno-inflammatory diseases in the United States. The company product pipeline includes Bosakitug (ATI-045), an anti-thymic stromal lymphopoietin monoclonal antibody in Phase 2 trial to treat moderate to severe atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, and moderate to severe chronic obstructive pulmonary disease; ATI-2138, an potent and selective novel investigational dual inhibitor of ITK and JAK3 in Phase 2a trial for the treatment for T cell-mediated autoimmune diseases; ATI-052, a humanized anti-TSLP and anti-IL4R bispecific antibody in Phase 1b to treat various atopic, immunologic, and respiratory diseases; ATI-9494, an oral, covalent, investigational dual inhibitor of ITK and Resting Lymphocyte Kinase (TXK), and other covalent JAK-sparing ITK inhibitors to treat modulate T cell biology across various diseases; and Lepzacitinib, a soft JAK 1/3 inhibitor for the treatment of atopic dermatitis and other dermatologic conditions.

Health Care · Biotechnology: Pharmaceutical Preparations · 69 employees

About Aquestive Therapeutics

AQST stock →

Aquestive Therapeutics, Inc. operates as a pharmaceutical company in the United States and internationally.

Health Care · Biotechnology: Pharmaceutical Preparations · 147 employees

ACRS vs AQST FAQ

Which is bigger, Aclaris Therapeutics or Aquestive Therapeutics?

Aquestive Therapeutics (AQST) is larger, with a market capitalization of $599.95M compared with $563.77M for Aclaris Therapeutics (ACRS).

Which stock has performed better over the past year, ACRS or AQST?

ACRS returned +96.41% over the past 12 months, compared with -28.55% for AQST (price return, excluding dividends). Past performance does not predict future results.

Are Aclaris Therapeutics and Aquestive Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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