MetaCap

Acrivon Therapeutics (ACRV) vs Heron Therapeutics (HRTX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Acrivon Therapeutics (ACRV) has outperformed Heron Therapeutics (HRTX) over the past year, losing 0.5% versus a loss of 73.5%. Acrivon Therapeutics is the larger company by market cap ($81.8 million vs $77.1 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ACRV-0.53%HRTX-73.47%
+67%-10%-87%
Oct 8, 20251 yearOct 8, 2026
ACRV-88.15%HRTX-87.90%
+46%-27%-100%
Nov 14, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ACRV versus HRTX key metrics
MetricACRVHRTX
Share price$1.91$0.4061
Market cap$81.85M$77.10M
1-day change+2.14%+13.37%
YTD return-22.41%-72.45%
1-year return-0.53%-73.47%
5-year return—-96.62%
EPS (TTM)$-1.88$-0.18
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$3.56$1.58
52-week low$1.27$0.26
Distance from 52-week high-46.35%-74.30%
Analyst consensusnonenone
Avg. price target upside+502.09%+1623.71%
Average volume356.18K2.59M
Shares outstanding42.85M189.85M
Employees74128
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ACRV has outperformed HRTX by 72.9 percentage points over the past year.

About Acrivon Therapeutics

ACRV stock →

Acrivon Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops oncology medicines for patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its generative phosphoproteomics platform. The company operates Acrivon Predictive Precision Proteomics (AP3), a precision medicine platform that enables the creation of drug specific proprietary OncoSignature companion diagnostics that are used to identify the patients to benefit from its drug candidates.

Health Care · Biotechnology: Pharmaceutical Preparations · 74 employees

About Heron Therapeutics

HRTX stock →

Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration.

Health Care · Biotechnology: Pharmaceutical Preparations · 128 employees

ACRV vs HRTX FAQ

Which is bigger, Acrivon Therapeutics or Heron Therapeutics?

Acrivon Therapeutics (ACRV) is larger, with a market capitalization of $81.85M compared with $77.10M for Heron Therapeutics (HRTX).

Which stock has performed better over the past year, ACRV or HRTX?

ACRV returned -0.53% over the past 12 months, compared with -73.47% for HRTX (price return, excluding dividends). Past performance does not predict future results.

Are Acrivon Therapeutics and Heron Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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