Actuate Therapeutics (ACTU) vs SeaStar Medical (ICU)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
SeaStar Medical (ICU) has outperformed Actuate Therapeutics (ACTU) over the past year, losing 47.0% versus a loss of 90.3%. SeaStar Medical is the larger company by market cap ($18.4 million vs $16.3 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ACTU | ICU |
|---|---|---|
| Share price | $0.679 | $3.49 |
| Market cap | $16.31M | $18.36M |
| 1-day change | -6.24% | -6.18% |
| YTD return | -88.91% | +45.42% |
| 1-year return | -90.31% | -47.04% |
| 5-year return | — | -99.86% |
| EPS (TTM) | $-0.87 | $-2.97 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $8.49 | $7.35 |
| 52-week low | $0.604 | $2.07 |
| Distance from 52-week high | -92.00% | -52.52% |
| Analyst consensus | none | none |
| Avg. price target upside | +1620.18% | +186.53% |
| Average volume | 386.51K | 99.80K |
| Shares outstanding | 24.01M | 5.26M |
| Employees | 12 | 18 |
| Sector | Healthcare | Healthcare |
| Industry | Biotechnology | Biotechnology |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ICU has outperformed ACTU by 43.3 percentage points over the past year.
About Actuate Therapeutics
ACTU stock →Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancers in the United States. The company's lead product candidate is elraglusib injection, a glycogen synthase kinase-3 inhibitor that is in Phase 2 trial to treat metastatic pancreatic ductal adenocarcinoma.
Healthcare · Biotechnology · 12 employees
About SeaStar Medical
ICU stock →SeaStar Medical Holding Corporation, a commercial-stage healthcare company, develops a proprietary platform therapy to reduce the consequences of hyperinflammation on vital organs in the United States. The company offers the selective cytopheretic device (SCD), which is a disease-modifying device that neutralizes over-active immune cells and stops the cytokine storm that yields destructive hyperinflammation; and QUELIMMUNE, an SCD therapy for pediatric patients with acute kidney injury (AKI) due to sepsis.
Healthcare · Biotechnology · 18 employees
ACTU vs ICU FAQ
Which is bigger, Actuate Therapeutics or SeaStar Medical?
SeaStar Medical (ICU) is larger, with a market capitalization of $18.36M compared with $16.31M for Actuate Therapeutics (ACTU).
Which stock has performed better over the past year, ACTU or ICU?
ICU returned -47.04% over the past 12 months, compared with -90.31% for ACTU (price return, excluding dividends). Past performance does not predict future results.
Are Actuate Therapeutics and SeaStar Medical in the same industry?
Yes. Both are classified in the Biotechnology industry within the Healthcare sector.