MetaCap

Adagene (ADAG) vs Tiziana Life Sciences (TLSA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 18, 2026.

Summary

Adagene (ADAG) has outperformed Tiziana Life Sciences (TLSA) over the past year, gaining 17.0% versus a loss of 46.2%. Over five years, TLSA leads with a -30.5% price change compared with -82.6% for ADAG. Adagene is the larger company by market cap ($138.3 million vs $133.6 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ADAG+17.05%TLSA-46.15%
+183%+56%-72%
Oct 17, 20251 yearOct 16, 2026
ADAG-82.39%TLSA-30.46%
+65%-17%-99%
Oct 11, 20215 yearsOct 12, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ADAG versus TLSA key metrics
MetricADAGTLSA
Share price$2.06$1.05
Market cap$138.32M$133.62M
1-day change-14.17%0.00%
YTD return+8.99%-29.53%
1-year return+17.05%-46.15%
5-year return-82.60%-30.46%
EPS (TTM)$-0.38$-0.21
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$7.67M—
Revenue growth (YoY)+7332.76%—
Net income (latest FY)$-17.61M$-11.86M
Operating margin-279.48%—
Net margin-229.56%—
52-week high$4.85$2.10
52-week low$1.30$0.76
Distance from 52-week high-57.53%-50.00%
Analyst consensusnonestrong_buy
Avg. price target upside+381.07%+667.62%
Average volume286.63K764.91K
Shares outstanding67.14M127.26M
Employees12810
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ADAG has outperformed TLSA by 63.2 percentage points over the past year.

About Adagene

ADAG stock →

Adagene Inc., a clinical stage biotechnology company, engages in the research, development, and production of monoclonal antibody drugs for cancers in the People's Republic of China. Its lead product candidate is the ADG126, a masked fully-human anti-CTLA-4 mAb which is in phase 1b/2 clinical development for the treatment of cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 128 employees

About Tiziana Life Sciences

TLSA stock →

Tiziana Life Sciences Ltd, together with its subsidiaries, engages in the research and development of therapies for neurodegenerative and neuroinflammatory diseases in the United Kingdom and internationally. It develops Foralumab TZLS-401, a human anti-CD3 monoclonal antibody, which is Phase II clinical trial for the treatment of non-active secondary progressive multiple sclerosis, Alzheimer's disease, multi system atrophy, and amyotrophic lateral sclerosis; and TZLS-501, a human anti-IL-6R monoclonal antibody for the treatment of autoimmune and inflammatory diseases.

Health Care · Biotechnology: Pharmaceutical Preparations · 10 employees

ADAG vs TLSA FAQ

Which is bigger, Adagene or Tiziana Life Sciences?

Adagene (ADAG) is larger, with a market capitalization of $138.32M compared with $133.62M for Tiziana Life Sciences (TLSA).

Which stock has performed better over the past year, ADAG or TLSA?

ADAG returned +17.05% over the past 12 months, compared with -46.15% for TLSA (price return, excluding dividends). Past performance does not predict future results.

Are Adagene and Tiziana Life Sciences in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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