MetaCap

Adaptive Biotechnologies (ADPT) vs Relay Therapeutics (RLAY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Relay Therapeutics (RLAY) has outperformed Adaptive Biotechnologies (ADPT) over the past year, gaining 184.9% versus a gain of 67.8%. Over five years, ADPT leads with a -22.1% price change compared with -49.0% for RLAY. Adaptive Biotechnologies is the larger company by market cap ($4.16 billion vs $3.82 billion), about 1.1 times the size.

Adaptive Biotechnologies converts more of its revenue into profit, with a net margin of -21.5% versus -1800.6%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ADPT+67.78%RLAY+184.94%
+253%+110%-33%
Oct 8, 20251 yearOct 8, 2026
ADPT-20.24%RLAY-38.17%
+32%-33%-99%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ADPT versus RLAY key metrics
MetricADPTRLAY
Share price$26.09$17.41
Market cap$4.16B$3.82B
1-day change-0.72%-3.01%
YTD return+60.65%+105.79%
1-year return+67.78%+184.94%
5-year return-22.12%-48.96%
EPS (TTM)$-0.41$-1.56
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$276.98M$15.36M
Revenue growth (YoY)+54.77%+53.44%
Net income (latest FY)$-59.50M$-276.48M
Gross margin74.24%—
Operating margin-20.62%-1971.59%
Net margin-21.48%-1800.58%
52-week high$30.74$21.27
52-week low$12.00$5.85
Distance from 52-week high-15.13%-18.15%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+8.51%+58.41%
Average volume2.38M2.80M
Shares outstanding159.60M219.14M
Employees624202
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • RLAY has outperformed ADPT by 117.2 percentage points over the past year.
  • Adaptive Biotechnologies is more profitable, keeping -21.5 cents of every revenue dollar as net income versus -1800.6 cents for Relay Therapeutics.

About Adaptive Biotechnologies

ADPT stock →

Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases. The company offers immunosequencing platform which combines a suite of proprietary chemistry, computational biology, and machine learning to generate clinical immunomics data to decode the adaptive immune system.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 624 employees

About Relay Therapeutics

RLAY stock →

Relay Therapeutics, Inc. operates as a clinical-stage precision medicines company.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 202 employees

ADPT vs RLAY FAQ

Which is bigger, Adaptive Biotechnologies or Relay Therapeutics?

Adaptive Biotechnologies (ADPT) is larger, with a market capitalization of $4.16B compared with $3.82B for Relay Therapeutics (RLAY).

Which stock has performed better over the past year, ADPT or RLAY?

RLAY returned +184.94% over the past 12 months, compared with +67.78% for ADPT (price return, excluding dividends). Past performance does not predict future results.

Are Adaptive Biotechnologies and Relay Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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