MetaCap

Agenus (AGEN) vs Kyverna Therapeutics (KYTX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Agenus (AGEN) has outperformed Kyverna Therapeutics (KYTX) over the past year, gaining 80.8% versus a loss of 13.9%. Kyverna Therapeutics is the larger company by market cap ($395.2 million vs $346.4 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AGEN+80.82%KYTX-13.93%
+147%+52%-42%
Oct 8, 20251 yearOct 8, 2026
AGEN-49.73%KYTX-79.47%
+17%-41%-99%
Feb 5, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AGEN versus KYTX key metrics
MetricAGENKYTX
Share price$7.67$6.39
Market cap$346.39M$395.18M
1-day change+1.72%+3.40%
YTD return+140.13%-34.26%
1-year return+80.82%-13.93%
5-year return-92.77%—
P/E ratio (TTM)3.03—
EPS (TTM)$2.53$-2.93
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$10.31$13.67
52-week low$2.71$5.96
Distance from 52-week high-25.61%-53.26%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+243.29%+375.74%
Average volume4.26M903.83K
Shares outstanding45.16M61.84M
Employees81149
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AGEN has outperformed KYTX by 94.7 percentage points over the past year.

About Agenus

AGEN stock →

Agenus Inc., a clinical-stage biotechnology company, discovers and develops immunotherapies for cancer and infectious diseases in the United States and internationally. It offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 81 employees

About Kyverna Therapeutics

KYTX stock →

Kyverna Therapeutics, Inc., a late-stage biopharmaceutical company, focuses on developing cell therapies for patients with autoimmune diseases. Its lead product candidate is KYV-101, an autologous CD19 CAR T-cell product candidate for the treatment of stiff person syndrome, myasthenia gravis, and autoimmune diseases.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 149 employees

AGEN vs KYTX FAQ

Which is bigger, Agenus or Kyverna Therapeutics?

Kyverna Therapeutics (KYTX) is larger, with a market capitalization of $395.18M compared with $346.39M for Agenus (AGEN).

Which stock has performed better over the past year, AGEN or KYTX?

AGEN returned +80.82% over the past 12 months, compared with -13.93% for KYTX (price return, excluding dividends). Past performance does not predict future results.

Are Agenus and Kyverna Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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