MetaCap

Agenus (AGEN) vs Rezolute (RZLT)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Agenus (AGEN) has outperformed Rezolute (RZLT) over the past year, gaining 80.8% versus a loss of 46.8%. Over five years, RZLT leads with a -30.2% price change compared with -92.8% for AGEN. Rezolute is the larger company by market cap ($471.0 million vs $346.4 million), about 1.4 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AGEN+80.82%RZLT-46.79%
+149%+27%-95%
Oct 8, 20251 yearOct 8, 2026
AGEN-93.28%RZLT-37.47%
+52%-27%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AGEN versus RZLT key metrics
MetricAGENRZLT
Share price$7.67$4.87
Market cap$346.39M$471.04M
1-day change+1.72%+4.96%
YTD return+140.13%+96.61%
1-year return+80.82%-46.79%
5-year return-92.77%-30.23%
P/E ratio (TTM)3.03—
EPS (TTM)$2.53$-0.75
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$10.31$11.46
52-week low$2.71$1.07
Distance from 52-week high-25.61%-57.49%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+243.29%+101.23%
Average volume4.26M1.50M
Shares outstanding45.16M96.72M
Employees8158
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AGEN has outperformed RZLT by 127.6 percentage points over the past year.

About Agenus

AGEN stock →

Agenus Inc., a clinical-stage biotechnology company, discovers and develops immunotherapies for cancer and infectious diseases in the United States and internationally. It offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 81 employees

About Rezolute

RZLT stock →

Rezolute, Inc., a late-stage rare disease company, focuses developing therapies that treat refractory and debilitating hypoglycemia associated with various forms of hyperinsulinism (HI) in the United States. Its lead clinical asset is ersodetug, an intravenously administered human monoclonal antibody which is in Phase 3 clinical trial to treat tumor HI indication, as well as congenital HI.

Health Care · Biotechnology: Pharmaceutical Preparations · 58 employees

AGEN vs RZLT FAQ

Which is bigger, Agenus or Rezolute?

Rezolute (RZLT) is larger, with a market capitalization of $471.04M compared with $346.39M for Agenus (AGEN).

Which stock has performed better over the past year, AGEN or RZLT?

AGEN returned +80.82% over the past 12 months, compared with -46.79% for RZLT (price return, excluding dividends). Past performance does not predict future results.

Are Agenus and Rezolute in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: Biological Products (No Diagnostic Substances) for Agenus and Biotechnology: Pharmaceutical Preparations for Rezolute.

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