MetaCap

Akebia Therapeutics (AKBA) vs PepGen (PEPG)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 18, 2026.

Summary

PepGen (PEPG) has outperformed Akebia Therapeutics (AKBA) over the past year, losing 46.8% versus a loss of 77.1%. Akebia Therapeutics is the larger company by market cap ($185.7 million vs $179.8 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AKBA-77.13%PEPG-46.83%
+53%-15%-83%
Oct 17, 20251 yearOct 16, 2026
AKBA+74.03%PEPG-79.83%
+982%+420%-143%
May 2, 20225 yearsOct 12, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AKBA versus PEPG key metrics
MetricAKBAPEPG
Share price$0.67$2.60
Market cap$185.66M$179.84M
1-day change-3.67%+2.77%
YTD return-58.39%-60.06%
1-year return-77.13%-46.83%
5-year return-76.98%—
EPS (TTM)$-0.12$-1.01
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$236.20M—
Revenue growth (YoY)+47.46%—
Net income (latest FY)$-5.34M$-89.66M
Gross margin83.29%—
Operating margin9.95%—
Net margin-2.26%—
52-week high$3.20$7.80
52-week low$0.6659$1.31
Distance from 52-week high-79.06%-66.67%
Analyst consensusnonestrong_buy
Avg. price target upside+485.07%+291.92%
Average volume6.70M864.38K
Shares outstanding277.11M69.17M
Employees19457
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PEPG has outperformed AKBA by 30.3 percentage points over the past year.

About Akebia Therapeutics

AKBA stock →

Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. Its product portfolio includes Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent (DD) and non-dialysis dependent (NDD) patients; and Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD and the treatment of iron deficiency anemia in adult patients with NDD-CKD.

Health Care · Biotechnology: Pharmaceutical Preparations · 194 employees

About PepGen

PEPG stock →

PepGen Inc., a clinical-stage biotechnology company, develops oligonucleotide therapeutics for the treatment of severe neuromuscular and neurologic diseases in the United States. The company engages in the development of PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 2 clinical trial for the treatment of myotonic dystrophy type 1; and FREEDOM2-DM1, which is in Phase 2 for the treatment of myotonic dystrophy type 1.

Health Care · Biotechnology: Pharmaceutical Preparations · 57 employees

AKBA vs PEPG FAQ

Which is bigger, Akebia Therapeutics or PepGen?

Akebia Therapeutics (AKBA) is larger, with a market capitalization of $185.66M compared with $179.84M for PepGen (PEPG).

Which stock has performed better over the past year, AKBA or PEPG?

PEPG returned -46.83% over the past 12 months, compared with -77.13% for AKBA (price return, excluding dividends). Past performance does not predict future results.

Are Akebia Therapeutics and PepGen in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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