MetaCap

Aldeyra Therapeutics (ALDX) vs Fractyl Health (GUTS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Fractyl Health (GUTS) has outperformed Aldeyra Therapeutics (ALDX) over the past year, losing 74.8% versus a loss of 83.1%. Fractyl Health is the larger company by market cap ($59.3 million vs $58.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ALDX-83.14%GUTS-74.82%
+77%-7%-91%
Oct 8, 20251 yearOct 8, 2026
ALDX-70.20%GUTS-97.26%
+128%+10%-108%
Jan 29, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ALDX versus GUTS key metrics
MetricALDXGUTS
Share price$0.964$4.47
Market cap$58.15M$59.29M
1-day change+1.72%+5.67%
YTD return-81.70%-83.98%
1-year return-83.14%-74.82%
5-year return-88.64%—
EPS (TTM)$-0.38$-10.56
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$5.93$29.34
52-week low$0.862$4.14
Distance from 52-week high-83.74%-84.76%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+584.65%+1251.23%
Average volume1.18M156.16K
Shares outstanding60.33M13.26M
Employees6100
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsMedical/Dental Instruments

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Aldeyra Therapeutics

ALDX stock →

Aldeyra Therapeutics, Inc., a biotechnology company, discovers and develops therapies designed to treat immune-mediated diseases. Its lead product candidate is reproxalap, a reactive aldehyde species (RASP) modulator, which is in Phase III clinical trial for the treatment of dry eye disease and allergic conjunctivitis; and ADX-2191, a dihydrofolate reductase inhibitor for the treatment of primary vitreoretinal lymphoma and retinitis pigmentosa.

Health Care · Biotechnology: Pharmaceutical Preparations · 6 employees

About Fractyl Health

GUTS stock →

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. It develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans.

Health Care · Medical/Dental Instruments · 100 employees

ALDX vs GUTS FAQ

Which is bigger, Aldeyra Therapeutics or Fractyl Health?

Fractyl Health (GUTS) is larger, with a market capitalization of $59.29M compared with $58.15M for Aldeyra Therapeutics (ALDX).

Which stock has performed better over the past year, ALDX or GUTS?

GUTS returned -74.82% over the past 12 months, compared with -83.14% for ALDX (price return, excluding dividends). Past performance does not predict future results.

Are Aldeyra Therapeutics and Fractyl Health in the same industry?

Both are in the Health Care sector, but in different industries: Biotechnology: Pharmaceutical Preparations for Aldeyra Therapeutics and Medical/Dental Instruments for Fractyl Health.

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