Alignment Healthcare (ALHC) vs CareDx (CDNA)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
CareDx (CDNA) has outperformed Alignment Healthcare (ALHC) over the past year, gaining 329.7% versus a loss of 49.6%. Over five years, CDNA leads with a -11.2% price change compared with -54.1% for ALHC. CareDx is the larger company by market cap ($3.22 billion vs $1.81 billion), about 1.8 times the size.
On valuation, Alignment Healthcare trades at a lower forward P/E (11.6x vs 48.2x for CareDx).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ALHC | CDNA |
|---|---|---|
| Share price | $8.71 | $62.21 |
| Market cap | $1.81B | $3.22B |
| 1-day change | +1.87% | -1.32% |
| YTD return | -56.71% | +234.61% |
| 1-year return | -49.65% | +329.72% |
| 5-year return | -54.08% | -11.21% |
| P/E ratio (TTM) | 45.84 | 29.91 |
| Forward P/E | 11.57 | 48.22 |
| EPS (TTM) | $0.19 | $2.08 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| Revenue (latest FY) | — | $379.81M |
| Revenue growth (YoY) | — | +13.79% |
| Net income (latest FY) | — | $-21.35M |
| Operating margin | — | -8.10% |
| Net margin | — | -5.62% |
| 52-week high | $25.12 | $72.51 |
| 52-week low | $7.37 | $13.95 |
| Distance from 52-week high | -65.33% | -14.21% |
| Analyst consensus | strong_buy | buy |
| Avg. price target upside | +135.82% | -5.43% |
| Average volume | 7.50M | 1.28M |
| Shares outstanding | 207.44M | 51.73M |
| Employees | 1,849 | 761 |
| Sector | Health Care | Health Care |
| Industry | Medical Specialities | Medical Specialities |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- CDNA has outperformed ALHC by 379.4 percentage points over the past year.
- Alignment Healthcare trades at a higher earnings multiple (45.8x vs 29.9x trailing P/E).
About Alignment Healthcare
ALHC stock →Alignment Healthcare, Inc. operates a consumer-centric healthcare platform for seniors in the United States.
Health Care · Medical Specialities · 1,849 employees
About CareDx
CDNA stock →CareDx, Inc. provides solutions for improving outcomes for transplant patients and advancing organ health in the United States and internationally.
Health Care · Medical Specialities · 761 employees
ALHC vs CDNA FAQ
Which is bigger, Alignment Healthcare or CareDx?
CareDx (CDNA) is larger, with a market capitalization of $3.22B compared with $1.81B for Alignment Healthcare (ALHC).
Which stock has performed better over the past year, ALHC or CDNA?
CDNA returned +329.72% over the past 12 months, compared with -49.65% for ALHC (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, ALHC or CDNA?
CDNA has the lower trailing P/E at 29.9, versus 45.8 for ALHC. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Alignment Healthcare and CareDx in the same industry?
Yes. Both are classified in the Medical Specialities industry within the Health Care sector.