MetaCap

Alumis (ALMS) vs Seaport Therapeutics (SPTX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Seaport Therapeutics is the larger company by market cap ($961.4 million vs $858.8 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ALMS-73.11%SPTX-9.63%
+46%-16%-79%
May 1, 20261 yearOct 7, 2026
ALMS-73.11%SPTX-9.63%
+30%-24%-78%
Apr 27, 20265 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ALMS versus SPTX key metrics
MetricALMSSPTX
Share price$6.64$17.96
Market cap$858.80M$961.41M
1-day change-1.99%+0.17%
YTD return-30.64%—
1-year return+50.11%—
EPS (TTM)$-3.86$-5.81
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$31.35$28.38
52-week low$4.28$14.85
Distance from 52-week high-78.84%-36.72%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+384.25%+113.20%
Average volume2.43M182.18K
Shares outstanding129.44M53.53M
Employees23758
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Alumis

ALMS stock →

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. The company offers envudeucitinib, a tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis and systemic lupus erythematosus; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor that is in Phase 1 for the treatment of neuroinflammatory and neurodegenerative diseases.

Health Care · Biotechnology: Pharmaceutical Preparations · 237 employees

About Seaport Therapeutics

SPTX stock →

Seaport Therapeutics, Inc., a clinical-stage therapeutics company, focuses on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. It is leveraging its proprietary Glyph platform to advance a pipeline of therapies to address the unmet needs in depression and anxiety.

Health Care · Biotechnology: Pharmaceutical Preparations · 58 employees

ALMS vs SPTX FAQ

Which is bigger, Alumis or Seaport Therapeutics?

Seaport Therapeutics (SPTX) is larger, with a market capitalization of $961.41M compared with $858.80M for Alumis (ALMS).

Are Alumis and Seaport Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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