MetaCap

ALX Oncology (ALXO) vs Cue Biopharma (CUE)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Cue Biopharma (CUE) has outperformed ALX Oncology (ALXO) over the past year, losing 13.2% versus a loss of 40.1%. Over five years, CUE leads with a -94.1% price change compared with -98.0% for ALXO. ALX Oncology is the larger company by market cap ($163.2 million vs $162.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ALXO-40.10%CUE-13.25%
+53%-16%-86%
Oct 8, 20251 yearOct 8, 2026
ALXO-98.07%CUE-94.34%
+32%-37%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ALXO versus CUE key metrics
MetricALXOCUE
Share price$1.18$22.33
Market cap$163.17M$162.21M
1-day change+4.42%-0.80%
YTD return+4.42%+144.04%
1-year return-40.10%-13.25%
5-year return-98.00%-94.09%
EPS (TTM)$-1.13$-29.59
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$2.66$45.50
52-week low$1.05$4.98
Distance from 52-week high-55.64%-50.92%
Analyst consensusnonestrong_buy
Avg. price target upside+289.83%+294.09%
Average volume1.04M267.15K
Shares outstanding138.28M7.26M
Employees4829
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • CUE has outperformed ALXO by 26.9 percentage points over the past year.

About ALX Oncology

ALXO stock →

ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for cancer patients in the United States. The company's lead product candidate is Evorpacept, a CD47 blocking therapeutic biologic development as a combination therapy with other anti-cancer agents, including ASPEN-06, under phase 2 clinical study for treating Gastric/GEJ cancer.

Health Care · Biotechnology: Pharmaceutical Preparations · 48 employees

About Cue Biopharma

CUE stock →

Cue Biopharma, Inc., a clinical-stage therapeutics company, focuses on developing various therapies for immunological disorders. The company's lead asset is CUE-221, an anti-IgE antibody with a dual-mechanism of action currently in Phase 2 development for allergic diseases.

Health Care · Biotechnology: Pharmaceutical Preparations · 29 employees

ALXO vs CUE FAQ

Which is bigger, ALX Oncology or Cue Biopharma?

ALX Oncology (ALXO) is larger, with a market capitalization of $163.17M compared with $162.21M for Cue Biopharma (CUE).

Which stock has performed better over the past year, ALXO or CUE?

CUE returned -13.25% over the past 12 months, compared with -40.10% for ALXO (price return, excluding dividends). Past performance does not predict future results.

Are ALX Oncology and Cue Biopharma in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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