Amphastar Pharmaceuticals (AMPH) vs Eton Pharmaceuticals (ETON)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Eton Pharmaceuticals (ETON) has outperformed Amphastar Pharmaceuticals (AMPH) over the past year, gaining 159.5% versus a loss of 1.1%. Over five years, ETON leads with a +953.4% price change compared with +33.6% for AMPH. Eton Pharmaceuticals is the larger company by market cap ($1.55 billion vs $1.09 billion), about 1.4 times the size.
On valuation, Amphastar Pharmaceuticals trades at a lower forward P/E (8.1x vs 21.0x for Eton Pharmaceuticals).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | AMPH | ETON |
|---|---|---|
| Share price | $25.67 | $54.18 |
| Market cap | $1.09B | $1.55B |
| 1-day change | +0.49% | -1.28% |
| YTD return | -4.63% | +224.54% |
| 1-year return | -1.12% | +159.48% |
| 5-year return | +33.65% | +953.36% |
| P/E ratio (TTM) | 15.19 | 135.45 |
| Forward P/E | 8.07 | 21.00 |
| EPS (TTM) | $1.69 | $0.40 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $29.52 | $66.37 |
| 52-week low | $16.65 | $14.27 |
| Distance from 52-week high | -13.06% | -18.37% |
| Analyst consensus | none | strong_buy |
| Avg. price target upside | -12.33% | +31.04% |
| Average volume | 472.61K | 606.07K |
| Shares outstanding | 42.54M | 28.58M |
| Employees | 1,976 | 44 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- ETON has outperformed AMPH by 160.6 percentage points over the past year.
- Eton Pharmaceuticals trades at a higher earnings multiple (135.4x vs 15.2x trailing P/E).
About Amphastar Pharmaceuticals
AMPH stock →Amphastar Pharmaceuticals, Inc., a bio-pharmaceutical company, develops, manufactures, markets, and sells generic and proprietary injectable, inhalation, and intranasal products in the United States, China, and France. It offers BAQSIMI, a dry nasal spray used in an emergency for the treatment of severe hypoglycemia; Primatene MIST, an epinephrine inhalation product for the temporary relief of mild symptoms of intermittent asthma; Glucagon for injection emergency kit; Enoxaparin, an injectable form of low molecular weight heparin for the prevention and treatment of deep vein thrombosis; and REXTOVY and Naloxone for opioid overdose.
Health Care · Biotechnology: Pharmaceutical Preparations · 1,976 employees
About Eton Pharmaceuticals
ETON stock →Eton Pharmaceuticals, Inc., a pharmaceutical company, focuses on developing and commercializing treatments for rare diseases. Its commercial rare disease products include Increlex for the treatment of severe primary igf-1 deficiency; Alkindi Sprinkle for adrenal insufficiency; Khindivi for adrenocortical insufficiency; Galzin for Wilson disease; PKU Golike for phenylketonuria; Carglumic Acid for N-acetylglutamate synthase deficiency; Betaine Anhydrous for homocystinuria; and Nitisinone for tyrosinemia type 1.
Health Care · Biotechnology: Pharmaceutical Preparations · 44 employees
AMPH vs ETON FAQ
Which is bigger, Amphastar Pharmaceuticals or Eton Pharmaceuticals?
Eton Pharmaceuticals (ETON) is larger, with a market capitalization of $1.55B compared with $1.09B for Amphastar Pharmaceuticals (AMPH).
Which stock has performed better over the past year, AMPH or ETON?
ETON returned +159.48% over the past 12 months, compared with -1.12% for AMPH (price return, excluding dividends). Past performance does not predict future results.
Which has the lower P/E ratio, AMPH or ETON?
AMPH has the lower trailing P/E at 15.2, versus 135.4 for ETON. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Amphastar Pharmaceuticals and Eton Pharmaceuticals in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.