MetaCap

Amarin (AMRN) vs Upstream Bio (UPB)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Amarin (AMRN) has outperformed Upstream Bio (UPB) over the past year, losing 37.6% versus a loss of 75.3%. Amarin is the larger company by market cap ($253.9 million vs $252.5 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AMRN-37.62%UPB-75.31%
+82%-0%-83%
Oct 7, 20251 yearOct 7, 2026
AMRN+1.86%UPB-79.05%
+74%-6%-86%
Oct 7, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AMRN versus UPB key metrics
MetricAMRNUPB
Share price$12.02$4.61
Market cap$253.90M$252.49M
1-day change-0.41%+0.44%
YTD return-13.90%-83.02%
1-year return-37.62%-75.31%
5-year return-88.35%—
Forward P/E12.27—
EPS (TTM)$-1.20$-2.88
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$20.90$33.68
52-week low$11.83$4.50
Distance from 52-week high-42.49%-86.31%
Analyst consensusnonenone
Avg. price target upside+3.99%+575.49%
Average volume66.16K610.08K
Shares outstanding21.12M54.77M
Employees8075
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • AMRN has outperformed UPB by 37.7 percentage points over the past year.

About Amarin

AMRN stock →

Amarin Corporation plc, a pharmaceutical company, engages in the commercialization and development of therapeutics for the treatment of cardiovascular diseases in the United States, Europe, and internationally. It offers VASCEPA, a prescription-only omega-3 fatty acid product, used as an adjunct to diet for reducing triglyceride levels in adult patients with severe hypertriglyceridemia.

Health Care · Biotechnology: Pharmaceutical Preparations · 80 employees

About Upstream Bio

UPB stock →

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 75 employees

AMRN vs UPB FAQ

Which is bigger, Amarin or Upstream Bio?

Amarin (AMRN) is larger, with a market capitalization of $253.90M compared with $252.49M for Upstream Bio (UPB).

Which stock has performed better over the past year, AMRN or UPB?

AMRN returned -37.62% over the past 12 months, compared with -75.31% for UPB (price return, excluding dividends). Past performance does not predict future results.

Are Amarin and Upstream Bio in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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