American Well (AMWL) vs OptimizeRx (OPRX)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
American Well (AMWL) has outperformed OptimizeRx (OPRX) over the past year, gaining 109.3% versus a loss of 52.4%. Over five years, OPRX leads with a -89.9% price change compared with -92.6% for AMWL. American Well is the larger company by market cap ($215.0 million vs $161.0 million), about 1.3 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | AMWL | OPRX |
|---|---|---|
| Share price | $12.64 | $8.55 |
| Market cap | $214.99M | $161.05M |
| 1-day change | +3.02% | -2.95% |
| YTD return | +157.43% | -30.26% |
| 1-year return | +109.27% | -52.37% |
| 5-year return | -92.56% | -89.90% |
| P/E ratio (TTM) | — | 35.63 |
| Forward P/E | — | 8.19 |
| EPS (TTM) | $-4.77 | $0.24 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $14.19 | $22.25 |
| 52-week low | $3.71 | $4.54 |
| Distance from 52-week high | -10.92% | -61.57% |
| Analyst consensus | none | strong_buy |
| Avg. price target upside | +1.27% | +47.37% |
| Average volume | 125.70K | 208.03K |
| Shares outstanding | 15.36M | 18.84M |
| Employees | 562 | 132 |
| Sector | Consumer Discretionary | Consumer Discretionary |
| Industry | Business Services | Business Services |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- AMWL has outperformed OPRX by 161.6 percentage points over the past year.
About American Well
AMWL stock →American Well Corporation, an enterprise platform and software company, delivers digitally enabling hybrid care in the United States and internationally. The company offers Amwell Platform, a cloud-based enablement platform, digitally enables a scalable healthcare experience across all care settings; Amwell Carepoint, a device enable healthcare providers to leverage proprietary carts and transform existing tablets and TVs into digital access points in clinical settings; Amwell Converge, a platform and wraparound services of digital care into the in-person, automated, and virtual care settings; and Behavioral Health, a platform that offer students and faculty the right level of care.
Consumer Discretionary · Business Services · 562 employees
About OptimizeRx
OPRX stock →OptimizeRx Corporation operates as a digital healthcare technology company. It offers Dynamic Audience Activation Platform, which generates dynamic audiences with predictive analytics through machine learning methods; Micro-Neighborhood Targeting, which creates consumer audiences using a privacy-first process; Profiler, which provides insights into its customers' target consumers; banner messages, including brand messaging, therapeutic support messaging, affordability messaging, limited distribution drug information, and patient support program messaging through healthcare professionals; and media execution solutions, which deliver messages through consumer omnichannel network, including through programmatic display, programmatic connected television/over-the-top, programmatic social media, addressable television, digital out-of-home, programmatic audio, and email/direct mail.
Consumer Discretionary · Business Services · 132 employees
AMWL vs OPRX FAQ
Which is bigger, American Well or OptimizeRx?
American Well (AMWL) is larger, with a market capitalization of $214.99M compared with $161.05M for OptimizeRx (OPRX).
Which stock has performed better over the past year, AMWL or OPRX?
AMWL returned +109.27% over the past 12 months, compared with -52.37% for OPRX (price return, excluding dividends). Past performance does not predict future results.
Are American Well and OptimizeRx in the same industry?
Yes. Both are classified in the Business Services industry within the Consumer Discretionary sector.