Annexon (ANNX) vs Design Therapeutics (DSGN)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.
Summary
Design Therapeutics (DSGN) has outperformed Annexon (ANNX) over the past year, gaining 80.1% versus a gain of 30.6%. Over five years, DSGN leads with a -18.0% price change compared with -81.8% for ANNX. Annexon is the larger company by market cap ($760.2 million vs $731.6 million), about 1.0 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ANNX | DSGN |
|---|---|---|
| Share price | $4.01 | $11.69 |
| Market cap | $760.21M | $731.58M |
| 1-day change | -0.50% | -2.34% |
| YTD return | -20.12% | +24.63% |
| 1-year return | +30.62% | +80.12% |
| 5-year return | -81.77% | -17.96% |
| EPS (TTM) | $-1.13 | $-1.18 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $7.18 | $17.25 |
| 52-week low | $2.54 | $5.28 |
| Distance from 52-week high | -44.15% | -32.23% |
| Average volume | 3.19M | 614.39K |
| Shares outstanding | 189.58M | 62.58M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- DSGN has outperformed ANNX by 49.5 percentage points over the past year.
ANNX vs DSGN FAQ
Which is bigger, Annexon or Design Therapeutics?
Annexon (ANNX) is larger, with a market capitalization of $760.21M compared with $731.58M for Design Therapeutics (DSGN).
Which stock has performed better over the past year, ANNX or DSGN?
DSGN returned +80.12% over the past 12 months, compared with +30.62% for ANNX (price return, excluding dividends). Past performance does not predict future results.
Are Annexon and Design Therapeutics in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.