MetaCap

AN2 Therapeutics (ANTX) vs Nkarta (NKTX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

AN2 Therapeutics (ANTX) has outperformed Nkarta (NKTX) over the past year, gaining 254.8% versus a loss of 4.7%. AN2 Therapeutics is the larger company by market cap ($166.0 million vs $161.2 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ANTX+254.84%NKTX-4.66%
+428%+190%-48%
Oct 9, 20251 yearOct 9, 2026
ANTX-71.43%NKTX-80.40%
+68%-17%-101%
Mar 21, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ANTX versus NKTX key metrics
MetricANTXNKTX
Share price$4.40$2.25
Market cap$166.04M$161.16M
1-day change-5.98%+1.35%
YTD return+285.96%+21.62%
1-year return+254.84%-4.66%
5-year return—-87.73%
EPS (TTM)$-0.99$-1.58
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.19$3.72
52-week low$1.00$1.70
Distance from 52-week high-38.80%-39.52%
Analyst consensusnonestrong_buy
Avg. price target upside+104.55%+381.33%
Average volume240.21K602.17K
Shares outstanding37.74M71.62M
Employees21106
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ANTX has outperformed NKTX by 259.5 percentage points over the past year.

About AN2 Therapeutics

ANTX stock →

AN2 Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics. The company's initial candidate includes epetraborole, which is phase 3 clinical trial as a once-daily oral treatment for patients with non-tuberculous mycobacterial lung disease, as well as studying for the treatment of acute melioidosis.

Health Care · Biotechnology: Pharmaceutical Preparations · 21 employees

About Nkarta

NKTX stock →

Nkarta, Inc., a clinical-stage biopharmaceutical company, develops and commercializes natural killer cell therapies for cancer and autoimmune disease treatment. Its lead product candidate is NKX019, a chimeric antigen receptor-natural killer (CAR NK) targeting the CD19 antigen, which is in Phase 1 clinical trial for the treatment of lupus nephritis; systemic sclerosis; idiopathic inflammatory myopathy; and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, as well as for systemic lupus erythematosus and myasthenia gravis.

Health Care · Biotechnology: Pharmaceutical Preparations · 106 employees

ANTX vs NKTX FAQ

Which is bigger, AN2 Therapeutics or Nkarta?

AN2 Therapeutics (ANTX) is larger, with a market capitalization of $166.04M compared with $161.16M for Nkarta (NKTX).

Which stock has performed better over the past year, ANTX or NKTX?

ANTX returned +254.84% over the past 12 months, compared with -4.66% for NKTX (price return, excluding dividends). Past performance does not predict future results.

Are AN2 Therapeutics and Nkarta in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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