MetaCap

Annovis Bio (ANVS) vs BioStem Technologies (BSEM)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

BioStem Technologies (BSEM) has outperformed Annovis Bio (ANVS) over the past year, losing 45.0% versus a loss of 48.5%. Over five years, BSEM leads with a +88.6% price change compared with -95.8% for ANVS. Annovis Bio is the larger company by market cap ($49.9 million vs $49.3 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ANVS-48.46%BSEM-45.00%
+134%+35%-63%
Oct 8, 20251 yearOct 8, 2026
ANVS-95.60%BSEM+95.56%
+1673%+747%-180%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ANVS versus BSEM key metrics
MetricANVSBSEM
Share price$1.17$2.64
Market cap$49.93M$49.29M
1-day change-3.31%+10.46%
YTD return-66.18%-30.71%
1-year return-48.46%-45.00%
5-year return-95.82%+88.57%
P/E ratio (TTM)—3.00
Forward P/E—9.10
EPS (TTM)$-1.75$0.88
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$5.50$8.40
52-week low$1.04$2.25
Distance from 52-week high-78.73%-68.57%
Analyst consensusnonenone
Avg. price target upside+797.44%+165.15%
Average volume884.63K124.14K
Shares outstanding42.68M18.67M
Employees773
SectorHealthcareHealthcare
IndustryBiotechnologyBiotechnology

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Annovis Bio

ANVS stock →

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's lead product candidate is Buntanetap, which is in phase 3 to treat alzheimer's disease, as well as in open-label phase 3 to treat parkinson's disease.

Healthcare · Biotechnology · 7 employees

About BioStem Technologies

BSEM stock →

BioStem Technologies, Inc. engages in the development, manufacturing, and commercialization of placental-derived allografts for advanced wound care and regenerative therapies in the United States.

Healthcare · Biotechnology · 73 employees

ANVS vs BSEM FAQ

Which is bigger, Annovis Bio or BioStem Technologies?

Annovis Bio (ANVS) is larger, with a market capitalization of $49.93M compared with $49.29M for BioStem Technologies (BSEM).

Which stock has performed better over the past year, ANVS or BSEM?

BSEM returned -45.00% over the past 12 months, compared with -48.46% for ANVS (price return, excluding dividends). Past performance does not predict future results.

Are Annovis Bio and BioStem Technologies in the same industry?

Yes. Both are classified in the Biotechnology industry within the Healthcare sector.

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