Annovis Bio (ANVS) vs Talphera (TLPH)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Talphera (TLPH) has outperformed Annovis Bio (ANVS) over the past year, losing 16.7% versus a loss of 46.5%. Over five years, TLPH leads with a -94.9% price change compared with -95.7% for ANVS. Talphera is the larger company by market cap ($54.0 million vs $48.7 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | ANVS | TLPH |
|---|---|---|
| Share price | $1.14 | $1.04 |
| Market cap | $48.65M | $53.98M |
| 1-day change | -5.79% | -0.95% |
| YTD return | -65.03% | -7.89% |
| 1-year return | -46.46% | -16.67% |
| 5-year return | -95.68% | -94.85% |
| EPS (TTM) | $-1.75 | $-0.26 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $5.50 | $1.57 |
| 52-week low | $1.04 | $0.69 |
| Distance from 52-week high | -79.27% | -33.76% |
| Average volume | 888.45K | 251.66K |
| Shares outstanding | 42.68M | 51.91M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TLPH has outperformed ANVS by 29.8 percentage points over the past year.
ANVS vs TLPH FAQ
Which is bigger, Annovis Bio or Talphera?
Talphera (TLPH) is larger, with a market capitalization of $53.98M compared with $48.65M for Annovis Bio (ANVS).
Which stock has performed better over the past year, ANVS or TLPH?
TLPH returned -16.67% over the past 12 months, compared with -46.46% for ANVS (price return, excluding dividends). Past performance does not predict future results.
Are Annovis Bio and Talphera in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.