MetaCap

Arcturus Therapeutics (ARCT) vs Fulcrum Therapeutics (FULC)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 18, 2026.

Summary

Arcturus Therapeutics (ARCT) has outperformed Fulcrum Therapeutics (FULC) over the past year, losing 50.0% versus a loss of 59.4%. Over five years, ARCT leads with a -76.8% price change compared with -85.3% for FULC. Arcturus Therapeutics is the larger company by market cap ($293.9 million vs $278.8 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ARCT-49.95%FULC-59.40%
+69%-5%-80%
Oct 17, 20251 yearOct 16, 2026
ARCT-77.30%FULC-85.96%
+8%-44%-96%
Oct 11, 20215 yearsOct 12, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ARCT versus FULC key metrics
MetricARCTFULC
Share price$10.34$3.65
Market cap$293.89M$278.79M
1-day change-8.25%-0.54%
YTD return+68.68%-67.73%
1-year return-49.95%-59.40%
5-year return-76.77%-85.26%
EPS (TTM)$-3.33$-1.21
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$82.03M$0
Revenue growth (YoY)-46.14%-100.00%
Net income (latest FY)$-65.78M$-74.88M
Operating margin-92.96%—
Net margin-80.19%—
52-week high$24.17$15.74
52-week low$5.50$2.83
Distance from 52-week high-57.22%-76.81%
Analyst consensusstrong_buynone
Avg. price target upside+130.17%+0.55%
Average volume941.87K1.52M
Shares outstanding28.42M76.38M
Employees1069
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Arcturus Therapeutics grew revenue faster in its latest fiscal year (-46.14% vs -100.00%).

About Arcturus Therapeutics

ARCT stock →

Arcturus Therapeutics Holdings Inc., a messenger RNA medicines company, focuses on the development of liver and respiratory rare disease therapeutics. Its technology platforms include STARR, a self-amplifying mRNA technology platform, and LUNAR, a lipid-mediated delivery system.

Health Care · Biotechnology: Pharmaceutical Preparations · 106 employees

About Fulcrum Therapeutics

FULC stock →

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia.

Health Care · Biotechnology: Pharmaceutical Preparations · 9 employees

ARCT vs FULC FAQ

Which is bigger, Arcturus Therapeutics or Fulcrum Therapeutics?

Arcturus Therapeutics (ARCT) is larger, with a market capitalization of $293.89M compared with $278.79M for Fulcrum Therapeutics (FULC).

Which stock has performed better over the past year, ARCT or FULC?

ARCT returned -49.95% over the past 12 months, compared with -59.40% for FULC (price return, excluding dividends). Past performance does not predict future results.

Are Arcturus Therapeutics and Fulcrum Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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