MetaCap

Arvinas (ARVN) vs ARS Pharmaceuticals (SPRY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Arvinas (ARVN) has outperformed ARS Pharmaceuticals (SPRY) over the past year, losing 23.0% versus a loss of 59.0%. Over five years, SPRY leads with a -53.8% price change compared with -91.2% for ARVN. Arvinas is the larger company by market cap ($484.6 million vs $453.5 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ARVN-22.97%SPRY-58.96%
+47%-11%-69%
Oct 8, 20251 yearOct 8, 2026
ARVN-90.87%SPRY-52.70%
+98%-2%-101%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ARVN versus SPRY key metrics
MetricARVNSPRY
Share price$7.51$4.56
Market cap$484.55M$453.48M
1-day change+0.81%+4.59%
YTD return-36.68%-60.86%
1-year return-22.97%-58.96%
5-year return-91.18%-53.75%
P/E ratio (TTM)28.88—
EPS (TTM)$0.26$-2.18
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$14.51$13.15
52-week low$6.97$3.99
Distance from 52-week high-48.24%-65.32%
Analyst consensusbuynone
Avg. price target upside+85.49%+393.42%
Average volume788.21K1.86M
Shares outstanding64.52M99.45M
Employees246195
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • ARVN has outperformed SPRY by 36.0 percentage points over the past year.

About Arvinas

ARVN stock →

Arvinas, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. The company develops proteolysis targeting chimeras (PROTAC) targeted protein degraders that are designed to harness the body's own natural protein disposal system to degrade and remove disease-causing proteins.

Health Care · Biotechnology: Pharmaceutical Preparations · 246 employees

About ARS Pharmaceuticals

SPRY stock →

ARS Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes treatments for severe allergic reactions in the United States and internationally. The company is involved in the development of neffy, a needle-free intranasal delivery of epinephrine for emergency treatment of Type I allergic reactions, including anaphylaxis.

Health Care · Biotechnology: Pharmaceutical Preparations · 195 employees

ARVN vs SPRY FAQ

Which is bigger, Arvinas or ARS Pharmaceuticals?

Arvinas (ARVN) is larger, with a market capitalization of $484.55M compared with $453.48M for ARS Pharmaceuticals (SPRY).

Which stock has performed better over the past year, ARVN or SPRY?

ARVN returned -22.97% over the past 12 months, compared with -58.96% for SPRY (price return, excluding dividends). Past performance does not predict future results.

Are Arvinas and ARS Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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