MetaCap

Astrotech (DE) (ASTC) vs Nautilus Biotechnology (NAUT)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Nautilus Biotechnology (NAUT) has outperformed Astrotech (DE) (ASTC) over the past year, gaining 126.3% versus a gain of 36.9%. Over five years, NAUT leads with a -65.7% price change compared with -76.7% for ASTC. Nautilus Biotechnology is the larger company by market cap ($239.2 million vs $14.6 million), about 16.4 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ASTC+36.93%NAUT+126.33%
+942%+419%-104%
Oct 7, 20251 yearOct 7, 2026
ASTC-77.13%NAUT-65.31%
+74%-13%-100%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ASTC versus NAUT key metrics
MetricASTCNAUT
Share price$6.95$1.88
Market cap$14.59M$239.24M
1-day change+1.24%-4.09%
YTD return+98.27%+0.51%
1-year return+36.93%+126.33%
5-year return-76.67%-65.67%
EPS (TTM)$-8.49$-0.45
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$68.85$4.31
52-week low$1.92$0.82
Distance from 52-week high-89.91%-56.38%
Analyst consensus—strong_buy
Avg. price target upside—+103.72%
Average volume130.50K2.59M
Shares outstanding2.10M127.26M
Employees—127
SectorIndustrialsIndustrials
IndustryBiotechnology: Laboratory Analytical InstrumentsBiotechnology: Laboratory Analytical Instruments

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Nautilus Biotechnology is about 16.4 times larger than Astrotech (DE) by market value ($239.24M vs $14.59M).
  • NAUT has outperformed ASTC by 89.4 percentage points over the past year.

About Nautilus Biotechnology

NAUT stock →

Nautilus Biotechnology, Inc., a development stage life sciences company, engages in creating a platform technology for quantifying and unlocking the complexity of the proteome in the United States. The company develops Nautilus Voyager Platform, which includes an end-to-end solution comprising instruments, reagents, consumables, and software analysis.

Industrials · Biotechnology: Laboratory Analytical Instruments · 127 employees

ASTC vs NAUT FAQ

Which is bigger, Astrotech (DE) or Nautilus Biotechnology?

Nautilus Biotechnology (NAUT) is larger, with a market capitalization of $239.24M compared with $14.59M for Astrotech (DE) (ASTC).

Which stock has performed better over the past year, ASTC or NAUT?

NAUT returned +126.33% over the past 12 months, compared with +36.93% for ASTC (price return, excluding dividends). Past performance does not predict future results.

Are Astrotech (DE) and Nautilus Biotechnology in the same industry?

Yes. Both are classified in the Biotechnology: Laboratory Analytical Instruments industry within the Industrials sector.

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