MetaCap

Anavex Life Sciences (AVXL) vs Outlook Therapeutics (OTLK)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

Outlook Therapeutics (OTLK) has outperformed Anavex Life Sciences (AVXL) over the past year, losing 51.3% versus a loss of 84.3%. Over five years, AVXL leads with a -91.5% price change compared with -98.6% for OTLK. Outlook Therapeutics is the larger company by market cap ($145.8 million vs $138.1 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

AVXL-84.35%OTLK-51.31%
+110%+8%-94%
Oct 9, 20251 yearOct 9, 2026
AVXL-91.35%OTLK-98.65%
+40%-33%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

AVXL versus OTLK key metrics
MetricAVXLOTLK
Share price$1.49$0.5989
Market cap$138.12M$145.80M
1-day change-3.25%+6.19%
YTD return-58.15%-62.09%
1-year return-84.35%-51.31%
5-year return-91.50%-98.58%
EPS (TTM)$-0.14$-0.74
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$9.50$2.54
52-week low$1.44$0.161
Distance from 52-week high-84.32%-76.40%
Analyst consensusnonenone
Avg. price target upside—+739.87%
Average volume983.35K13.43M
Shares outstanding92.70M243.45M
Employees3417
SectorHealth CareHealthcare
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • OTLK has outperformed AVXL by 33.0 percentage points over the past year.
  • The two companies sit in different sectors: Anavex Life Sciences in Health Care and Outlook Therapeutics in Healthcare.

About Anavex Life Sciences

AVXL stock →

Anavex Life Sciences Corp. operates as a biopharmaceutical company.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 34 employees

About Outlook Therapeutics

OTLK stock →

Outlook Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company, focuses on developing and commercializing monoclonal antibodies for ophthalmic indications. Its lead product candidate is ONS-5010, an ophthalmic bevacizumab product formulation of bevacizumab product candidate that is in Phase-III clinical trial for the treatment of wet age-related macular degeneration and other retina diseases.

Healthcare · Biotechnology · 17 employees

AVXL vs OTLK FAQ

Which is bigger, Anavex Life Sciences or Outlook Therapeutics?

Outlook Therapeutics (OTLK) is larger, with a market capitalization of $145.80M compared with $138.12M for Anavex Life Sciences (AVXL).

Which stock has performed better over the past year, AVXL or OTLK?

OTLK returned -51.31% over the past 12 months, compared with -84.35% for AVXL (price return, excluding dividends). Past performance does not predict future results.

Are Anavex Life Sciences and Outlook Therapeutics in the same industry?

No. Anavex Life Sciences is in the Health Care sector, while Outlook Therapeutics is in Healthcare.

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