Aytu BioPharma (AYTU) vs TherapeuticsMD (TXMD)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
TherapeuticsMD (TXMD) has outperformed Aytu BioPharma (AYTU) over the past year, gaining 85.2% versus a loss of 13.1%. Over five years, TXMD leads with a -94.4% price change compared with -96.1% for AYTU. TherapeuticsMD is the larger company by market cap ($23.3 million vs $22.3 million), about 1.0 times the size.
On valuation, TherapeuticsMD trades at a lower forward P/E (5.7x vs 13.2x for Aytu BioPharma).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | AYTU | TXMD |
|---|---|---|
| Share price | $2.05 | $2.01 |
| Market cap | $22.28M | $23.26M |
| 1-day change | 0.00% | +0.50% |
| YTD return | -21.15% | +22.70% |
| 1-year return | -13.14% | +85.19% |
| 5-year return | -96.13% | -94.44% |
| Forward P/E | 13.23 | 5.74 |
| EPS (TTM) | $-1.16 | $-0.04 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.07 | $2.95 |
| 52-week low | $1.80 | $1.03 |
| Distance from 52-week high | -33.22% | -31.86% |
| Average volume | 34.40K | 23.94K |
| Shares outstanding | 10.87M | 11.57M |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations | Biotechnology: Pharmaceutical Preparations |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- TXMD has outperformed AYTU by 98.3 percentage points over the past year.
AYTU vs TXMD FAQ
Which is bigger, Aytu BioPharma or TherapeuticsMD?
TherapeuticsMD (TXMD) is larger, with a market capitalization of $23.26M compared with $22.28M for Aytu BioPharma (AYTU).
Which stock has performed better over the past year, AYTU or TXMD?
TXMD returned +85.19% over the past 12 months, compared with -13.14% for AYTU (price return, excluding dividends). Past performance does not predict future results.
Are Aytu BioPharma and TherapeuticsMD in the same industry?
Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.