MetaCap

Biofrontera (BFRI) vs Universe Pharmaceuticals (UPC)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Biofrontera (BFRI) has outperformed Universe Pharmaceuticals (UPC) over the past year, losing 9.0% versus a loss of 55.8%. Universe Pharmaceuticals is the larger company by market cap ($20.0 million vs $14.3 million), about 1.4 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

BFRI-9.03%UPC-55.81%
+66%-8%-83%
Oct 8, 20251 yearOct 8, 2026
BFRI-98.96%UPC-99.95%
+214%+49%-115%
Oct 25, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

BFRI versus UPC key metrics
MetricBFRIUPC
Share price$0.9652$3.99
Market cap$14.34M$20.05M
1-day change+5.05%-3.86%
YTD return+61.19%+9.71%
1-year return-9.03%-55.81%
5-year return—-99.95%
Forward P/E2.24—
EPS (TTM)$-0.43$-1.38
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$1.66$17.96
52-week low$0.555$2.00
Distance from 52-week high-41.86%-77.78%
Analyst consensusnone—
Avg. price target upside+521.63%—
Average volume547.45K788.87K
Shares outstanding14.85M5.01M
Employees84216
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • BFRI has outperformed UPC by 46.8 percentage points over the past year.

About Biofrontera

BFRI stock →

Biofrontera Inc., a biopharmaceutical company, engages in the commercialization of pharmaceutical products for the treatment of dermatological conditions in the United States. It offers Ameluz, BF-RhodoLED, RhodoLED XL lamp series, and RhodoLED Lamps, which are used for the treatment of actinic keratosis, which are pre-cancerous skin lesions.

Health Care · Biotechnology: Pharmaceutical Preparations · 84 employees

About Universe Pharmaceuticals

UPC stock →

Universe Pharmaceuticals INC, through its subsidiaries, engages in the manufacturing, marketing, distribution, and sales of traditional Chinese medicine derivative products in China. The company offers products for the treatment and relief of common chronic health conditions in the elderly for physical wellness and longevity; and cold and flu medications.

Health Care · Biotechnology: Pharmaceutical Preparations · 216 employees

BFRI vs UPC FAQ

Which is bigger, Biofrontera or Universe Pharmaceuticals?

Universe Pharmaceuticals (UPC) is larger, with a market capitalization of $20.05M compared with $14.34M for Biofrontera (BFRI).

Which stock has performed better over the past year, BFRI or UPC?

BFRI returned -9.03% over the past 12 months, compared with -55.81% for UPC (price return, excluding dividends). Past performance does not predict future results.

Are Biofrontera and Universe Pharmaceuticals in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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