Biote (BTMD) vs 22nd Century Group (XXII)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.
Summary
Biote is the larger company by market cap ($39.7 million vs $621,674), about 63.8 times the size. On valuation, 22nd Century Group trades at a lower trailing P/E (0.0x vs 8.4x for Biote).
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | BTMD | XXII |
|---|---|---|
| Share price | $1.17 | $0.8707 |
| Market cap | $39.66M | $621.67K |
| 1-day change | +5.41% | -2.33% |
| YTD return | -55.00% | — |
| 1-year return | -59.23% | — |
| 5-year return | -88.02% | — |
| P/E ratio (TTM) | 8.36 | 0.01 |
| Forward P/E | 2.60 | — |
| EPS (TTM) | $0.14 | $78.07 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $3.26 | $540.00 |
| 52-week low | $1.06 | $0.785 |
| Distance from 52-week high | -64.11% | -99.84% |
| Analyst consensus | none | — |
| Avg. price target upside | +123.08% | — |
| Average volume | 230.14K | 98.47K |
| Shares outstanding | 28.68M | 713.99K |
| Employees | 223 | 32 |
| Sector | Health Care | Health Care |
| Industry | Medicinal Chemicals and Botanical Products | Medicinal Chemicals and Botanical Products |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- Biote is about 63.8 times larger than 22nd Century Group by market value ($39.66M vs $621.67K).
- Biote trades at a higher earnings multiple (8.4x vs 0.0x trailing P/E).
About Biote
BTMD stock →biote Corp. operates in practice-building business within the hormone optimization space.
Health Care · Medicinal Chemicals and Botanical Products · 223 employees
About 22nd Century Group
XXII stock →22nd Century Group, Inc., a tobacco products company, manufactures, distributes, and sells proprietary new reduced nicotine tobacco products in the United States. The company offers reduced nicotine content tobacco and very low nicotine combustible cigarette products.
Health Care · Medicinal Chemicals and Botanical Products · 32 employees
BTMD vs XXII FAQ
Which is bigger, Biote or 22nd Century Group?
Biote (BTMD) is larger, with a market capitalization of $39.66M compared with $621.67K for 22nd Century Group (XXII).
Which has the lower P/E ratio, BTMD or XXII?
XXII has the lower trailing P/E at 0.0, versus 8.4 for BTMD. A lower P/E is not by itself a sign of a better investment; it can reflect slower expected growth or higher risk.
Are Biote and 22nd Century Group in the same industry?
Yes. Both are classified in the Medicinal Chemicals and Botanical Products industry within the Health Care sector.