Cabaletta Bio (CABA) vs Orchestra BioMed (OBIO)
Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.
Summary
Orchestra BioMed (OBIO) has outperformed Cabaletta Bio (CABA) over the past year, gaining 107.3% versus a loss of 15.1%. Over five years, OBIO leads with a -42.5% price change compared with -83.9% for CABA. Orchestra BioMed is the larger company by market cap ($348.6 million vs $326.4 million), about 1.1 times the size.
Summary generated from market data by MetaCap's automated system. Methodology
Relative performance
Percent change in share price from the first common trading day shown; excludes dividends.
Head-to-head
| Metric | CABA | OBIO |
|---|---|---|
| Share price | $1.93 | $5.80 |
| Market cap | $326.37M | $348.61M |
| 1-day change | -2.28% | +2.47% |
| YTD return | -10.05% | +36.39% |
| 1-year return | -15.09% | +107.33% |
| 5-year return | -83.93% | -42.54% |
| EPS (TTM) | $-1.51 | $-0.86 |
| Dividend yield | 0.00% | 0.00% |
| Annual dividend | $0.00 | $0.00 |
| 52-week high | $4.23 | $6.50 |
| 52-week low | $1.83 | $2.78 |
| Distance from 52-week high | -54.49% | -10.77% |
| Analyst consensus | none | strong_buy |
| Avg. price target upside | +588.31% | +114.31% |
| Average volume | 4.67M | 299.24K |
| Shares outstanding | 169.55M | 60.11M |
| Employees | 154 | 86 |
| Sector | Health Care | Health Care |
| Industry | Biotechnology: Biological Products (No Diagnostic Substances) | Medicinal Chemicals and Botanical Products |
Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.
Key differences
- OBIO has outperformed CABA by 122.4 percentage points over the past year.
About Cabaletta Bio
CABA stock →Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with autoimmune diseases. The company's lead product candidate is resecabtagene autoleucel, a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T, which is in Phase 1/2 clinical trials for the treatment of dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, juvenile myositis, lupus nephritis, systemic lupus erythematosus, relapsing and progressive multiple sclerosis, mucocutaneous and mucosal pemphigus vulgaris (PV), systemic sclerosis, and generalized myasthenia gravis.
Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 154 employees
About Orchestra BioMed
OBIO stock →Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States.
Health Care · Medicinal Chemicals and Botanical Products · 86 employees
CABA vs OBIO FAQ
Which is bigger, Cabaletta Bio or Orchestra BioMed?
Orchestra BioMed (OBIO) is larger, with a market capitalization of $348.61M compared with $326.37M for Cabaletta Bio (CABA).
Which stock has performed better over the past year, CABA or OBIO?
OBIO returned +107.33% over the past 12 months, compared with -15.09% for CABA (price return, excluding dividends). Past performance does not predict future results.
Are Cabaletta Bio and Orchestra BioMed in the same industry?
Both are in the Health Care sector, but in different industries: Biotechnology: Biological Products (No Diagnostic Substances) for Cabaletta Bio and Medicinal Chemicals and Botanical Products for Orchestra BioMed.