MetaCap

Crescent Biopharma (CBIO) vs Evolus (EOLS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Evolus (EOLS) has outperformed Crescent Biopharma (CBIO) over the past year, gaining 23.6% versus a gain of 19.5%. Over five years, EOLS leads with a +0.9% price change compared with -93.2% for CBIO. Crescent Biopharma is the larger company by market cap ($523.8 million vs $506.6 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CBIO+19.49%EOLS+23.64%
+148%+51%-46%
Oct 7, 20251 yearOct 7, 2026
CBIO-92.94%EOLS+13.49%
+169%+31%-108%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CBIO versus EOLS key metrics
MetricCBIOEOLS
Share price$14.10$7.67
Market cap$523.77M$506.61M
1-day change+4.52%-0.90%
YTD return+13.74%+16.39%
1-year return+19.49%+23.64%
5-year return-93.19%+0.91%
Forward P/E—26.22
EPS (TTM)$-7.63$-0.53
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$27.41$9.31
52-week low$8.72$3.86
Distance from 52-week high-48.56%-17.62%
Analyst consensusstrong_buynone
Avg. price target upside+123.40%+95.57%
Average volume397.58K896.67K
Shares outstanding37.14M66.05M
Employees69353
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Crescent Biopharma

CBIO stock →

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003.

Health Care · Biotechnology: Pharmaceutical Preparations · 69 employees

About Evolus

EOLS stock →

Evolus, Inc., a performance beauty company, delivers products in the cash-pay aesthetic market in the United States, Canada, Europe, and Australia. It offers Jeuveau, a proprietary 900 kilodalton purified botulinum toxin type A formulation for the temporary improvement in the appearance of moderate to severe glabellar lines in adults; and Evolysse, a collection of injectable hyaluronic acid gels, which includes various products, such as mid face, nasolabial folds, lips and eyes.

Health Care · Biotechnology: Pharmaceutical Preparations · 353 employees

CBIO vs EOLS FAQ

Which is bigger, Crescent Biopharma or Evolus?

Crescent Biopharma (CBIO) is larger, with a market capitalization of $523.77M compared with $506.61M for Evolus (EOLS).

Which stock has performed better over the past year, CBIO or EOLS?

EOLS returned +23.64% over the past 12 months, compared with +19.49% for CBIO (price return, excluding dividends). Past performance does not predict future results.

Are Crescent Biopharma and Evolus in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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