MetaCap

Crescent Biopharma (CBIO) vs Oculis (OCS)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Crescent Biopharma (CBIO) has outperformed Oculis (OCS) over the past year, gaining 17.1% versus a loss of 56.4%. Over five years, OCS leads with a -11.8% price change compared with -92.9% for CBIO. Oculis is the larger company by market cap ($533.4 million vs $524.5 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CBIO+17.08%OCS-56.42%
+133%+33%-66%
Oct 8, 20251 yearOct 8, 2026
CBIO-92.61%OCS-11.81%
+249%+69%-112%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CBIO versus OCS key metrics
MetricCBIOOCS
Share price$14.12$8.66
Market cap$524.51M$533.35M
1-day change+4.67%+1.88%
YTD return+19.06%-56.63%
1-year return+17.08%-56.42%
5-year return-92.87%-11.81%
EPS (TTM)$-7.63$-1.74
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$27.41$34.48
52-week low$8.72$8.30
Distance from 52-week high-48.49%-74.88%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+123.09%+321.36%
Average volume399.18K257.00K
Shares outstanding37.14M61.59M
Employees6960
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • CBIO has outperformed OCS by 73.5 percentage points over the past year.

About Crescent Biopharma

CBIO stock →

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003.

Health Care · Biotechnology: Pharmaceutical Preparations · 69 employees

About Oculis

OCS stock →

Oculis Holding AG, a clinical-stage biopharmaceutical company, develops drug candidates to treat ophthalmic, neuro-ophthalmic, and neurological diseases in Switzerland and internationally. The company's lead product candidate is OCS-01, a topical dexamethasone optireach formulation, which is in Phase 3 clinical trials for the treatment of diabetic macular edema; OCS-02, a topical biologic candidate that is in Phase 2b clinical trials for the treatment for dry eye disease; and OCS-05, a disease modifying neuroprotective agent for neurological damage with indications for glaucoma, dry age-related macular degeneration and diabetic retinopathy, and acute optic neuritis.

Health Care · Biotechnology: Pharmaceutical Preparations · 60 employees

CBIO vs OCS FAQ

Which is bigger, Crescent Biopharma or Oculis?

Oculis (OCS) is larger, with a market capitalization of $533.35M compared with $524.51M for Crescent Biopharma (CBIO).

Which stock has performed better over the past year, CBIO or OCS?

CBIO returned +17.08% over the past 12 months, compared with -56.42% for OCS (price return, excluding dividends). Past performance does not predict future results.

Are Crescent Biopharma and Oculis in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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