MetaCap

Celldex Therapeutics (CLDX) vs QuidelOrtho (QDEL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Celldex Therapeutics (CLDX) has outperformed QuidelOrtho (QDEL) over the past year, gaining 7.6% versus a loss of 55.5%. Over five years, CLDX leads with a -36.6% price change compared with -90.3% for QDEL. Celldex Therapeutics is the larger company by market cap ($2.30 billion vs $851.0 million), about 2.7 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CLDX+7.56%QDEL-55.46%
+71%+0%-71%
Oct 8, 20251 yearOct 8, 2026
CLDX-45.90%QDEL-91.01%
+23%-38%-98%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CLDX versus QDEL key metrics
MetricCLDXQDEL
Share price$29.30$12.41
Market cap$2.30B$851.02M
1-day change-3.71%+0.81%
YTD return+7.88%-56.55%
1-year return+7.56%-55.46%
5-year return-36.55%-90.32%
Forward P/E—8.61
EPS (TTM)$-4.35$-15.39
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$1.54M—
Revenue growth (YoY)-77.99%—
Net income (latest FY)$-258.76M—
Gross margin87.06%—
Operating margin-18599.81%—
Net margin-16748.03%—
52-week high$45.14$35.58
52-week low$22.10$9.92
Distance from 52-week high-35.09%-65.12%
Analyst consensusstrong_buyhold
Avg. price target upside+115.26%+18.21%
Average volume1.32M1.51M
Shares outstanding78.53M68.58M
Employees1986,500
SectorHealth CareHealth Care
IndustryBiotechnology: In Vitro & In Vivo Diagnostic SubstancesBiotechnology: In Vitro & In Vivo Diagnostic Substances

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Celldex Therapeutics is about 2.7 times larger than QuidelOrtho by market value ($2.30B vs $851.02M).
  • CLDX has outperformed QDEL by 63.0 percentage points over the past year.

About Celldex Therapeutics

CLDX stock →

Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic antibodies for patients with severe inflammatory, allergic, autoimmune, and other diseases. The company's drug candidates include monoclonal and bispecific antibodies designed to address mast cell mediated diseases for which available treatments are inadequate.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 198 employees

About QuidelOrtho

QDEL stock →

QuidelOrtho Corporation provides diagnostic testing solutions. The company operates through Labs, Transfusion Medicine, Point of Care, and Molecular Diagnostics business units.

Health Care · Biotechnology: In Vitro & In Vivo Diagnostic Substances · 6,500 employees

CLDX vs QDEL FAQ

Which is bigger, Celldex Therapeutics or QuidelOrtho?

Celldex Therapeutics (CLDX) is larger, with a market capitalization of $2.30B compared with $851.02M for QuidelOrtho (QDEL).

Which stock has performed better over the past year, CLDX or QDEL?

CLDX returned +7.56% over the past 12 months, compared with -55.46% for QDEL (price return, excluding dividends). Past performance does not predict future results.

Are Celldex Therapeutics and QuidelOrtho in the same industry?

Yes. Both are classified in the Biotechnology: In Vitro & In Vivo Diagnostic Substances industry within the Health Care sector.

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