MetaCap

Clene (CLNN) vs Edesa Biotech (EDSA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Edesa Biotech (EDSA) has outperformed Clene (CLNN) over the past year, gaining 34.6% versus a loss of 58.8%. Over five years, EDSA leads with a -93.3% price change compared with -96.9% for CLNN. Clene is the larger company by market cap ($55.2 million vs $49.5 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CLNN-58.81%EDSA+34.56%
+604%+251%-103%
Oct 8, 20251 yearOct 8, 2026
CLNN-97.17%EDSA-93.18%
+12%-46%-104%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CLNN versus EDSA key metrics
MetricCLNNEDSA
Share price$3.88$3.66
Market cap$55.15M$49.45M
1-day change-1.02%-5.79%
YTD return-33.90%+157.75%
1-year return-58.81%+34.56%
5-year return-96.86%-93.31%
EPS (TTM)$-3.52$-1.72
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$13.50$20.32
52-week low$3.25$0.72
Distance from 52-week high-71.26%-81.99%
Analyst consensusnonenone
Avg. price target upside+729.90%+346.17%
Average volume100.21K61.89K
Shares outstanding14.21M13.51M
Employees7617
SectorConsumer DefensiveHealthcare
IndustryPackaged FoodsBiotechnology

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • EDSA has outperformed CLNN by 93.4 percentage points over the past year.
  • The two companies sit in different sectors: Clene in Consumer Defensive and Edesa Biotech in Healthcare.

About Clene

CLNN stock →

Clene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The company's lead drug candidate is CNM-Au8, which is being studied in various clinical trials, including a completed Phase 2 platform trial to evaluate the safety and efficacy of CNM-Au8 in patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; completed Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a second Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases.

Consumer Defensive · Packaged Foods · 76 employees

About Edesa Biotech

EDSA stock →

Edesa Biotech, Inc., a clinical-stage biopharmaceutical company, engages in the research and development, manufacture, and commercialization of pharmaceutical products for inflammatory and immune-related diseases. It develops EB05, a monoclonal antibody, which is in Phase 3 clinical study for the treatment of acute respiratory distress syndrome; and EB01, a topical vanishing cream containing non-steroidal anti-inflammatory compound that has completed Phase 3 clinical study to treat chronic allergic contact dermatitis.

Healthcare · Biotechnology · 17 employees

CLNN vs EDSA FAQ

Which is bigger, Clene or Edesa Biotech?

Clene (CLNN) is larger, with a market capitalization of $55.15M compared with $49.45M for Edesa Biotech (EDSA).

Which stock has performed better over the past year, CLNN or EDSA?

EDSA returned +34.56% over the past 12 months, compared with -58.81% for CLNN (price return, excluding dividends). Past performance does not predict future results.

Are Clene and Edesa Biotech in the same industry?

No. Clene is in the Consumer Defensive sector, while Edesa Biotech is in Healthcare.

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