MetaCap

ClearPoint Neuro (CLPT) vs Quantum-Si (QSI)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Quantum-Si (QSI) has outperformed ClearPoint Neuro (CLPT) over the past year, losing 31.1% versus a loss of 64.6%. Over five years, CLPT leads with a -41.6% price change compared with -85.8% for QSI. ClearPoint Neuro is the larger company by market cap ($320.0 million vs $267.0 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CLPT-64.56%QSI-31.07%
+55%-11%-77%
Oct 8, 20251 yearOct 8, 2026
CLPT-38.48%QSI-85.35%
+68%-15%-99%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CLPT versus QSI key metrics
MetricCLPTQSI
Share price$10.49$1.22
Market cap$319.99M$267.04M
1-day change-1.59%-4.69%
YTD return-23.32%+10.91%
1-year return-64.56%-31.07%
5-year return-41.59%-85.81%
EPS (TTM)$-1.18$-0.45
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$29.35$3.10
52-week low$8.27$0.69
Distance from 52-week high-64.26%-60.65%
Analyst consensusstrong_buybuy
Avg. price target upside+124.02%+86.89%
Average volume642.92K4.15M
Shares outstanding30.50M198.95M
Employees160145
SectorHealth CareIndustrials
IndustryMedical/Dental InstrumentsIndustrial Machinery/Components

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • QSI has outperformed CLPT by 33.5 percentage points over the past year.
  • The two companies sit in different sectors: ClearPoint Neuro in Health Care and Quantum-Si in Industrials.

About ClearPoint Neuro

CLPT stock →

ClearPoint Neuro, Inc., a commercial-stage medical device company, focuses on the development and commercialization of platforms for performing minimally invasive surgical procedures in the brain in the United States. The company offers ClearPoint systems, such as ClearPoint hardware, which includes head fixation frame, computer workstation, and in-room monitor; and ClearPoint disposables, which consist of SmartFrame trajectory device, a hand controller and related accessories, and its SmartFlow Neuro cannula.

Health Care · Medical/Dental Instruments · 160 employees

About Quantum-Si

QSI stock →

Quantum-Si incorporated, a life sciences company, develops proprietary, universal, and single-molecule detection platform applied to proteomics to enable next-gen protein sequencing (NGPS). The company offers Platinum and Platinum Pro NGPS instruments for single-molecule, amino acid level resolution, and automated data analysis; library preparation kits to prepare a customer's protein sample for sequencing; and sequencing kits, which contain the reagents and consumables used to perform NGPS.

Industrials · Industrial Machinery/Components · 145 employees

CLPT vs QSI FAQ

Which is bigger, ClearPoint Neuro or Quantum-Si?

ClearPoint Neuro (CLPT) is larger, with a market capitalization of $319.99M compared with $267.04M for Quantum-Si (QSI).

Which stock has performed better over the past year, CLPT or QSI?

QSI returned -31.07% over the past 12 months, compared with -64.56% for CLPT (price return, excluding dividends). Past performance does not predict future results.

Are ClearPoint Neuro and Quantum-Si in the same industry?

No. ClearPoint Neuro is in the Health Care sector, while Quantum-Si is in Industrials.

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