MetaCap

Compass Therapeutics (CMPX) vs Cardiol Therapeutics (CRDL)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Cardiol Therapeutics (CRDL) has outperformed Compass Therapeutics (CMPX) over the past year, gaining 24.5% versus a loss of 71.7%. Over five years, CRDL leads with a -66.4% price change compared with -68.2% for CMPX. Compass Therapeutics is the larger company by market cap ($177.2 million vs $160.4 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CMPX-71.75%CRDL+24.53%
+125%+20%-86%
Oct 7, 20251 yearOct 7, 2026
CMPX-70.00%CRDL-59.63%
+101%+3%-94%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CMPX versus CRDL key metrics
MetricCMPXCRDL
Share price$0.984$1.32
Market cap$177.21M$160.40M
1-day change-3.53%0.00%
YTD return-81.01%+38.36%
1-year return-71.75%+24.53%
5-year return-68.22%-66.41%
EPS (TTM)$-0.39$-0.25
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$6.88$2.34
52-week low$0.829$0.88
Distance from 52-week high-85.70%-43.59%
Analyst consensusbuystrong_buy
Avg. price target upside+453.86%+533.33%
Average volume4.06M1.44M
Shares outstanding180.09M121.51M
Employees3918
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • CRDL has outperformed CMPX by 96.3 percentage points over the past year.

About Compass Therapeutics

CMPX stock →

Compass Therapeutics, Inc., a clinical-stage oncology-focused biopharmaceutical company, develops antibody-based therapeutics for the treatment of various human diseases in the United States. The company's lead product candidate, tovecimig, is a bispecific antibody that targets delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A), which are critical to angiogenesis and tumor vascularization.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 39 employees

About Cardiol Therapeutics

CRDL stock →

Cardiol Therapeutics Inc., a clinical-stage life sciences company, focuses on the development of anti-fibrotic and anti-inflammatory therapies for the treatment of heart diseases. Its lead product candidate is CardiolRx, which is in Phase III multi-national, randomized, double-blind, and placebo-controlled study to evaluate the efficacy and safety of CardiolRx in acute myocarditis, as well as for the treatment of recurrent pericarditis.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 18 employees

CMPX vs CRDL FAQ

Which is bigger, Compass Therapeutics or Cardiol Therapeutics?

Compass Therapeutics (CMPX) is larger, with a market capitalization of $177.21M compared with $160.40M for Cardiol Therapeutics (CRDL).

Which stock has performed better over the past year, CMPX or CRDL?

CRDL returned +24.53% over the past 12 months, compared with -71.75% for CMPX (price return, excluding dividends). Past performance does not predict future results.

Are Compass Therapeutics and Cardiol Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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