MetaCap

Collegium Pharmaceutical (COLL) vs Verastem (VSTM)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Verastem (VSTM) has outperformed Collegium Pharmaceutical (COLL) over the past year, losing 8.2% versus a loss of 34.3%. Over five years, COLL leads with a +4.5% price change compared with -75.0% for VSTM. Verastem is the larger company by market cap ($748.5 million vs $713.9 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

COLL-34.32%VSTM-8.17%
+55%-6%-67%
Oct 7, 20251 yearOct 7, 2026
COLL+8.08%VSTM-75.58%
+158%+26%-105%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

COLL versus VSTM key metrics
MetricCOLLVSTM
Share price$21.93$8.27
Market cap$713.94M$748.51M
1-day change+0.23%+6.65%
YTD return-52.63%+7.06%
1-year return-34.32%-8.17%
5-year return+4.53%-75.05%
P/E ratio (TTM)17.27—
Forward P/E3.30—
EPS (TTM)$1.27$-2.45
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$50.79$10.82
52-week low$21.43$3.43
Distance from 52-week high-56.82%-23.61%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+123.44%+77.50%
Average volume747.73K2.26M
Shares outstanding32.56M90.56M
Employees423102
SectorHealthcareHealthcare
IndustryDrug Manufacturers - Specialty & GenericBiotechnology

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • VSTM has outperformed COLL by 26.2 percentage points over the past year.

About Collegium Pharmaceutical

COLL stock →

Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. The company's portfolio includes Jornay PM, a central nervous system stimulant prescription medicine that contains methylphenidate HCl for the treatment of attention deficit hyperactivity disorder; Belbuca, a buccal film that contains buprenorphine for severe and persistent pain that requires an extended treatment period; Xtampza ER, an abuse-deterrent, extended-release, oral formulation of oxycodone for the management of pain severe enough to require daily; Nucynta ER and Nucynta IR, which are extended-release and immediate-release oral formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; and Symproic, an oral formulation of naldemedine for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain.

Healthcare · Drug Manufacturers - Specialty & Generic · 423 employees

About Verastem

VSTM stock →

Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States. Its product candidates are Avutometinib, which is an orally administered, small molecule dual RAF/MEK inhibitor developed to block MEK kinase activity and the compensatory reactivation of MEK by upstream RAF, thereby targeting the RAS/MAPK signaling pathway that is commonly activated in various cancers; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine kinase for various solid tumors.

Healthcare · Biotechnology · 102 employees

COLL vs VSTM FAQ

Which is bigger, Collegium Pharmaceutical or Verastem?

Verastem (VSTM) is larger, with a market capitalization of $748.51M compared with $713.94M for Collegium Pharmaceutical (COLL).

Which stock has performed better over the past year, COLL or VSTM?

VSTM returned -8.17% over the past 12 months, compared with -34.32% for COLL (price return, excluding dividends). Past performance does not predict future results.

Are Collegium Pharmaceutical and Verastem in the same industry?

Both are in the Healthcare sector, but in different industries: Drug Manufacturers - Specialty & Generic for Collegium Pharmaceutical and Biotechnology for Verastem.

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