MetaCap

Coya Therapeutics (COYA) vs Unicycive Therapeutics (UNCY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Unicycive Therapeutics (UNCY) has outperformed Coya Therapeutics (COYA) over the past year, losing 14.7% versus a loss of 20.9%. Coya Therapeutics is the larger company by market cap ($116.4 million vs $113.0 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

COYA-20.92%UNCY-14.68%
+85%+20%-46%
Oct 8, 20251 yearOct 8, 2026
COYA+5.32%UNCY-24.63%
+418%+177%-65%
Dec 26, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

COYA versus UNCY key metrics
MetricCOYAUNCY
Share price$4.96$4.13
Market cap$116.35M$113.00M
1-day change-0.60%+1.35%
YTD return-13.97%-29.46%
1-year return-20.92%-14.68%
5-year return—-85.06%
Forward P/E—2.45
EPS (TTM)$-1.07$-1.72
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$7.75$8.74
52-week low$3.71$3.93
Distance from 52-week high-36.00%-52.80%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+206.65%+588.48%
Average volume158.05K839.29K
Shares outstanding23.46M27.39M
Employees821
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Coya Therapeutics

COYA stock →

Coya Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of proprietary therapies to enhance the function of regulatory T cells (Tregs). Its candidate product pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy.

Health Care · Biotechnology: Pharmaceutical Preparations · 8 employees

About Unicycive Therapeutics

UNCY stock →

Unicycive Therapeutics, Inc., a clinical-stage biotechnology company, identifies, develops, and commercializes therapies for the treatment of kidney diseases in the United States. It develops oxylanthanum carbonate, a lanthanum-based phosphate binding agent, which is for the treatment of hyperphosphatemia in patients with chronic kidney disease on dialysis; and UNI-494, a nicotinamide ester derivative and a selective ATP-sensitive mitochondrial potassium channel activator, which is in Phase I clinical trial for the treatment of acute kidney injury and pre-clinical stage for the treatment of chronic kidney disease.

Health Care · Biotechnology: Pharmaceutical Preparations · 21 employees

COYA vs UNCY FAQ

Which is bigger, Coya Therapeutics or Unicycive Therapeutics?

Coya Therapeutics (COYA) is larger, with a market capitalization of $116.35M compared with $113.00M for Unicycive Therapeutics (UNCY).

Which stock has performed better over the past year, COYA or UNCY?

UNCY returned -14.68% over the past 12 months, compared with -20.92% for COYA (price return, excluding dividends). Past performance does not predict future results.

Are Coya Therapeutics and Unicycive Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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