MetaCap

Castle Biosciences (CSTL) vs Fortrea (FTRE)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 9, 2026.

Summary

Fortrea (FTRE) has outperformed Castle Biosciences (CSTL) over the past year, gaining 101.1% versus a gain of 42.9%. Fortrea is the larger company by market cap ($1.94 billion vs $1.04 billion), about 1.9 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CSTL+42.90%FTRE+101.09%
+115%+43%-30%
Oct 8, 20251 yearOct 8, 2026
CSTL+155.77%FTRE-32.33%
+236%+67%-102%
Jun 12, 20235 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CSTL versus FTRE key metrics
MetricCSTLFTRE
Share price$34.17$20.44
Market cap$1.04B$1.94B
1-day change+1.36%+0.34%
YTD return-13.34%+18.09%
1-year return+42.90%+101.09%
5-year return-46.98%—
Forward P/E—17.85
EPS (TTM)$-0.64$-0.91
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)—$2.72B
Revenue growth (YoY)—+1.00%
Net income (latest FY)—$-986.20M
Gross margin—18.50%
Operating margin—-32.04%
Net margin—-36.21%
52-week high$44.28$23.51
52-week low$17.72$8.55
Distance from 52-week high-22.83%-13.06%
Analyst consensusstrong_buybuy
Avg. price target upside+32.02%+1.91%
Average volume402.90K1.49M
Shares outstanding30.55M95.10M
Employees1,00214,000
SectorHealth CareHealth Care
IndustryMedical SpecialitiesMedical Specialities

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • FTRE has outperformed CSTL by 58.2 percentage points over the past year.

About Castle Biosciences

CSTL stock →

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions.

Health Care · Medical Specialities · 1,002 employees

About Fortrea

FTRE stock →

Fortrea Holdings Inc., a contract research organization, provides biopharmaceutical product and medical device development solutions to pharmaceutical, biotechnology, and medical device customers worldwide. It offers clinical pharmacology, such as clinical research units, external partnerships, project management, study design and monitoring, bioanalytics and biomarkers, pharmacokinetics, modeling and simulation, and biometrics; and clinical development, including phase I through IV clinical and real-world evidence studies, regulatory affairs, protocol design, operational planning, study and site start-up, patient recruitment, project management, comprehensive site and medical monitoring, data management and biostatistics, pharmacovigilance, medical writing, and mobile clinical services.

Health Care · Medical Specialities · 14,000 employees

CSTL vs FTRE FAQ

Which is bigger, Castle Biosciences or Fortrea?

Fortrea (FTRE) is larger, with a market capitalization of $1.94B compared with $1.04B for Castle Biosciences (CSTL).

Which stock has performed better over the past year, CSTL or FTRE?

FTRE returned +101.09% over the past 12 months, compared with +42.90% for CSTL (price return, excluding dividends). Past performance does not predict future results.

Are Castle Biosciences and Fortrea in the same industry?

Yes. Both are classified in the Medical Specialities industry within the Health Care sector.

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