MetaCap

Contineum Therapeutics (CTNM) vs Puma Biotechnology (PBYI)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 10, 2026.

Summary

Puma Biotechnology (PBYI) has outperformed Contineum Therapeutics (CTNM) over the past year, gaining 97.5% versus a gain of 10.0%. Puma Biotechnology is the larger company by market cap ($531.2 million vs $503.4 million), about 1.1 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

CTNM+10.03%PBYI+97.50%
+104%+36%-31%
Oct 9, 20251 yearOct 9, 2026
CTNM-13.12%PBYI+81.80%
+90%+2%-85%
Apr 1, 20245 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

CTNM versus PBYI key metrics
MetricCTNMPBYI
Share price$13.38$10.29
Market cap$503.37M$531.17M
1-day change+1.52%+3.21%
YTD return+17.06%+72.94%
1-year return+10.03%+97.50%
5-year return—+70.08%
P/E ratio (TTM)—20.18
Forward P/E—29.40
EPS (TTM)$-1.73$0.51
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$17.79$10.35
52-week low$8.60$4.58
Distance from 52-week high-24.77%-0.58%
Analyst consensusstrong_buynone
Avg. price target upside+67.64%—
Average volume520.62K320.35K
Shares outstanding32.96M51.62M
Employees51179
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • PBYI has outperformed CTNM by 87.5 percentage points over the past year.

About Contineum Therapeutics

CTNM stock →

Contineum Therapeutics, Inc., a clinical stage biopharmaceutical company, engages in developing of small molecules different therapies for neuroscience, inflammation, and immunology indications in the United States. The company's lead asset is PIPE-791, a novel, brain penetrant, small molecule inhibitor of the lysophosphatidic acid 1 receptor (LPA1R) for the treatment of idiopathic pulmonary fibrosis and chronic pain.

Health Care · Biotechnology: Pharmaceutical Preparations · 51 employees

About Puma Biotechnology

PBYI stock →

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine.

Health Care · Biotechnology: Pharmaceutical Preparations · 179 employees

CTNM vs PBYI FAQ

Which is bigger, Contineum Therapeutics or Puma Biotechnology?

Puma Biotechnology (PBYI) is larger, with a market capitalization of $531.17M compared with $503.37M for Contineum Therapeutics (CTNM).

Which stock has performed better over the past year, CTNM or PBYI?

PBYI returned +97.50% over the past 12 months, compared with +10.03% for CTNM (price return, excluding dividends). Past performance does not predict future results.

Are Contineum Therapeutics and Puma Biotechnology in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

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