MetaCap

Definium Therapeutics (DFTX) vs Tilray Brands (TLRY)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 7, 2026.

Summary

Definium Therapeutics (DFTX) has outperformed Tilray Brands (TLRY) over the past year, gaining 193.1% versus a loss of 78.3%. Over five years, DFTX leads with a -0.5% price change compared with -96.4% for TLRY. Definium Therapeutics is the larger company by market cap ($4.71 billion vs $549.0 million), about 8.6 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

DFTX+187.15%TLRY-76.49%
+315%+110%-96%
Oct 6, 20251 yearOct 7, 2026
DFTX+4.43%TLRY-96.46%
+47%-28%-103%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

DFTX versus TLRY key metrics
MetricDFTXTLRY
Share price$35.09$3.72
Market cap$4.71B$549.01M
1-day change-1.49%-1.72%
YTD return+162.06%-58.86%
1-year return+193.15%-78.27%
5-year return-0.45%-96.37%
Forward P/E—20.92
EPS (TTM)$-3.43$-1.10
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Net income (latest FY)$-183.79M—
52-week high$49.70$23.20
52-week low$10.47$3.54
Distance from 52-week high-29.40%-83.99%
Analyst consensusnone—
Avg. price target upside+104.19%—
Average volume2.15M4.08M
Shares outstanding134.37M147.78M
Employees105—
SectorHealth CareHealth Care
Industry Medicinal Chemicals and Botanical Products Medicinal Chemicals and Botanical Products

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • Definium Therapeutics is about 8.6 times larger than Tilray Brands by market value ($4.71B vs $549.01M).
  • DFTX has outperformed TLRY by 271.4 percentage points over the past year.

About Definium Therapeutics

DFTX stock →

Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder.

Health Care · Medicinal Chemicals and Botanical Products · 105 employees

DFTX vs TLRY FAQ

Which is bigger, Definium Therapeutics or Tilray Brands?

Definium Therapeutics (DFTX) is larger, with a market capitalization of $4.71B compared with $549.01M for Tilray Brands (TLRY).

Which stock has performed better over the past year, DFTX or TLRY?

DFTX returned +193.15% over the past 12 months, compared with -78.27% for TLRY (price return, excluding dividends). Past performance does not predict future results.

Are Definium Therapeutics and Tilray Brands in the same industry?

Yes. Both are classified in the Medicinal Chemicals and Botanical Products industry within the Health Care sector.

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