MetaCap

Dianthus Therapeutics (DNTH) vs Travere Therapeutics (TVTX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Dianthus Therapeutics (DNTH) has outperformed Travere Therapeutics (TVTX) over the past year, gaining 144.6% versus a gain of 109.6%. Over five years, TVTX leads with a +118.1% price change compared with -21.2% for DNTH. Travere Therapeutics is the larger company by market cap ($4.86 billion vs $4.56 billion), about 1.1 times the size.

Travere Therapeutics converts more of its revenue into profit, with a net margin of -5.2% versus -7973.3%.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

DNTH+144.61%TVTX+109.57%
+246%+115%-17%
Oct 7, 20251 yearOct 7, 2026
DNTH-23.23%TVTX+103.43%
+164%+29%-107%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

DNTH versus TVTX key metrics
MetricDNTHTVTX
Share price$81.51$51.59
Market cap$4.56B$4.86B
1-day change-3.98%-3.46%
YTD return+105.97%+39.86%
1-year return+144.61%+109.57%
5-year return-21.17%+118.12%
Forward P/E—9.15
EPS (TTM)$-4.24$-0.74
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
Revenue (latest FY)$2.04M$490.73M
Revenue growth (YoY)-67.35%+110.45%
Net income (latest FY)$-162.34M$-25.55M
Gross margin—97.89%
Operating margin-8739.34%-12.80%
Net margin-7973.33%-5.21%
52-week high$117.88$68.73
52-week low$32.22$22.59
Distance from 52-week high-30.86%-24.94%
Analyst consensusstrong_buystrong_buy
Avg. price target upside+72.75%+45.78%
Average volume821.22K1.58M
Shares outstanding55.93M94.26M
Employees92497
SectorHealth CareHealth Care
IndustryBiotechnology: Pharmaceutical PreparationsBiotechnology: Pharmaceutical Preparations

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • DNTH has outperformed TVTX by 35.0 percentage points over the past year.
  • Travere Therapeutics is more profitable, keeping -5.2 cents of every revenue dollar as net income versus -7973.3 cents for Dianthus Therapeutics.
  • Travere Therapeutics grew revenue faster in its latest fiscal year (+110.45% vs -67.35%).

About Dianthus Therapeutics

DNTH stock →

Dianthus Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoimmune diseases. Its lead clinical-stage candidate, claseprubart, a monoclonal antibody engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein; and DNTH212, a bifunctional fusion protein that targets plasmacytoid dendritic cell (pDC) BDCA2 to reduce Type 1 interferon production, while simultaneously inhibiting BAFF/APRIL to suppress B cell function.

Health Care · Biotechnology: Pharmaceutical Preparations · 92 employees

About Travere Therapeutics

TVTX stock →

Travere Therapeutics, Inc., a biopharmaceutical company, identifies, develops, and delivers therapies to people living with rare kidney and metabolic diseases in the United States. The company's products include FILSPARI (sparsentan), a once-daily, oral medication designed to target two critical pathways in the disease progression of IgA Nephropathy (endothelin 1 and angiotensin-II); and Thiola and Thiola EC (tiopronin tablets) for the treatment of cystinuria, a rare genetic cystine transport disorder that causes high cystine levels in the urine and the formation of recurring kidney stones.

Health Care · Biotechnology: Pharmaceutical Preparations · 497 employees

DNTH vs TVTX FAQ

Which is bigger, Dianthus Therapeutics or Travere Therapeutics?

Travere Therapeutics (TVTX) is larger, with a market capitalization of $4.86B compared with $4.56B for Dianthus Therapeutics (DNTH).

Which stock has performed better over the past year, DNTH or TVTX?

DNTH returned +144.61% over the past 12 months, compared with +109.57% for TVTX (price return, excluding dividends). Past performance does not predict future results.

Are Dianthus Therapeutics and Travere Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Pharmaceutical Preparations industry within the Health Care sector.

More comparisons