MetaCap

Dyadic International (DYAI) vs Scilex (SCLX)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Dyadic International (DYAI) has outperformed Scilex (SCLX) over the past year, losing 60.7% versus a loss of 73.0%. Over five years, DYAI leads with a -90.8% price change compared with -98.6% for SCLX. Scilex is the larger company by market cap ($20.8 million vs $17.8 million), about 1.2 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

DYAI-61.02%SCLX-73.92%
+34%-22%-79%
Oct 7, 20251 yearOct 8, 2026
DYAI-91.34%SCLX-98.64%
+41%-32%-106%
Oct 4, 20215 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

DYAI versus SCLX key metrics
MetricDYAISCLX
Share price$0.4444$2.96
Market cap$17.80M$20.82M
1-day change-2.65%-15.19%
YTD return-52.72%-61.03%
1-year return-60.67%-72.96%
5-year return-90.84%-98.65%
Forward P/E—4.05
EPS (TTM)$-0.23$-49.70
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$1.60$16.81
52-week low$0.34$2.62
Distance from 52-week high-72.23%-82.39%
Average volume202.50K53.62K
Shares outstanding40.06M7.03M
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

Key differences

  • DYAI has outperformed SCLX by 12.3 percentage points over the past year.

DYAI vs SCLX FAQ

Which is bigger, Dyadic International or Scilex?

Scilex (SCLX) is larger, with a market capitalization of $20.82M compared with $17.80M for Dyadic International (DYAI).

Which stock has performed better over the past year, DYAI or SCLX?

DYAI returned -60.67% over the past 12 months, compared with -72.96% for SCLX (price return, excluding dividends). Past performance does not predict future results.

Are Dyadic International and Scilex in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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