MetaCap

enGene Therapeutics (ENGN) vs Tenaya Therapeutics (TNYA)

Head-to-head comparison of performance, valuation, growth, profitability and dividends. Prices delayed 15 minutes; data as of Oct 8, 2026.

Summary

Tenaya Therapeutics (TNYA) has outperformed enGene Therapeutics (ENGN) over the past year, losing 69.9% versus a loss of 75.1%. Tenaya Therapeutics is the larger company by market cap ($122.0 million vs $119.3 million), about 1.0 times the size.

Summary generated from market data by MetaCap's automated system. Methodology

Relative performance

ENGN-75.11%TNYA-69.86%
+81%-3%-87%
Oct 7, 20251 yearOct 7, 2026
ENGN-82.30%TNYA-95.84%
+203%+46%-111%
Jan 31, 20225 yearsOct 5, 2026

Percent change in share price from the first common trading day shown; excludes dividends.

Head-to-head

ENGN versus TNYA key metrics
MetricENGNTNYA
Share price$1.78$0.5442
Market cap$119.29M$122.03M
1-day change+2.01%+2.02%
YTD return-80.68%-25.08%
1-year return-75.11%-69.86%
5-year return—-97.41%
EPS (TTM)$-2.07$-0.52
Dividend yield0.00%0.00%
Annual dividend$0.00$0.00
52-week high$12.25$2.35
52-week low$1.40$0.5211
Distance from 52-week high-85.47%-76.84%
Analyst consensus—strong_buy
Avg. price target upside—+488.02%
Average volume746.58K2.26M
Shares outstanding67.02M224.23M
Employees—70
SectorHealth CareHealth Care
IndustryBiotechnology: Biological Products (No Diagnostic Substances)Biotechnology: Biological Products (No Diagnostic Substances)

Highlighted cells mark the higher value for growth, returns, margins and yield, and the lower value for P/E ratios. Highlighting is a mechanical comparison, not a recommendation.

About Tenaya Therapeutics

TNYA stock →

Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial.

Health Care · Biotechnology: Biological Products (No Diagnostic Substances) · 70 employees

ENGN vs TNYA FAQ

Which is bigger, enGene Therapeutics or Tenaya Therapeutics?

Tenaya Therapeutics (TNYA) is larger, with a market capitalization of $122.03M compared with $119.29M for enGene Therapeutics (ENGN).

Which stock has performed better over the past year, ENGN or TNYA?

TNYA returned -69.86% over the past 12 months, compared with -75.11% for ENGN (price return, excluding dividends). Past performance does not predict future results.

Are enGene Therapeutics and Tenaya Therapeutics in the same industry?

Yes. Both are classified in the Biotechnology: Biological Products (No Diagnostic Substances) industry within the Health Care sector.

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